Social Media Ideas for Noncoding Variants

Latest updates for Noncoding Variants

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bioengineer.org /1 month ago

Scientists characterize genetic variants across the human intrinsically disordered proteome

Variant effect prediction has entered a new phase, but one of biology’s largest blind spots remains stubbornly difficult to resolve. Computational tools have become increasingly ef...

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rna-seqblog.com /4 weeks ago

RNA variant imaging for cancer diagnosis

RNA Variant Imaging is attracting attention because it addresses a persistent blind spot in cancer diagnostics: many clinically relevant RNA isoforms, splice events, and fusion tra...

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rna-seqblog.com /1 week ago

Overlooked DNA regions surrounding ‘microexons’ hold missing pieces of autism’s genetic puzzle

RNA sequencing and machine learning revealed more than 1,500 previously unidentified microexons and genetic variants affecting their splicing, providing new insights into autism-as...

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journals.plos.org /2 weeks ago

HiFIseek: Gene-specific enrichment of high-impact mutations in associated genomic regions

by Rafael Riudavets Puig, Denise G. O’Mahony, Ina Skaara Brorson, Ksenia Sokolova, Vessela N. Kristensen, Anthony Mathelier Transcription is regulated through the sequence-specifi...

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journals.plos.org /3 weeks ago

The prevalence of protein misfolding as a mechanism for hereditary deafness

by Rose A. Gogal, Genevieve M. Cox, Diana L. Kolbe, Amanda M. Odell, Chloe E. Ovel, Katherine I. McCormick, Brian Hong, Hela Azaiez, Thomas L. Casavant, Richard J. H. Smith, Terry...

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bioengineer.org /4 days ago

Non-coding RNAs emerge as diagnostic and therapeutic leads in abdominal aortic aneurysm

A new review maps how microRNAs, long non-coding RNAs and circular RNAs regulate the biological processes driving abdominal aortic aneurysm and could serve as future biomarkers and...

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journals.plos.org /6 days ago

<i>NLGN3</i> autism variants have distinct functional impact on synapses and sleep behavior in <i>Dros...

by Rebekah E. Townsley, Jonathan C. Andrews, Saurabh Srivastav, Sharayu V. Jangam, Shabab B. Hannan, Oguz Kanca, Paul C. Marcogliese, Shinya Yamamoto, Michael F. Wangler Neuroligi...

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genengnews.com /1 week ago

Newly Identified Microexons Offer Clues to Autism Spectrum Disorder’s Genetic Roots

Hundreds of newly identified microexons seem to matter for autism and other neurological conditions, according to a Nature study. A machine learning model of their regulatory code...

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