Search results for Lncrna

Long Non-Coding RNA May be a Promising Therapeutic Target for Cancer

RNA sequencing reveals how lncRNA IGF1R-AS1 drives MYC activation through chromatin looping, promoting tumor progression and highlighting a potential therapeutic target in prostate...

Multi-Omics Uncover Diverse Rice lncRNA Effects

In a groundbreaking study published in Cell Research, researchers have leveraged population-scale multi-omics approaches to uncover the extensive and nuanced roles of long non-codi...

Targeting novel long non-coding RNA may improve glioblastoma treatment

RNA sequencing reveals a novel long non-coding RNA driving glioblastoma growth and treatment resistance, offering new targets to improve response to EGFR inhibitor therapies...

longcallR – SNP calling, haplotype phasing and allele-specific analysis with long RNA-seq reads

RNA sequencing with long-read technology links genetic variants to transcript structure, uncovering allele-specific splicing and previously unannotated RNA events across human samp...

Single-cell total RNA sequencing expands our view of gene regulation

RNA sequencing captures both coding and noncoding RNAs at single-cell resolution, revealing complex regulatory programs and cellular identities across development and disease...

tRNA-Derived 3′U-tRFSerTGA Signals Poor Myeloma Prognosis

In a groundbreaking study published in the British Journal of Cancer, researchers have uncovered a novel molecular player in the complex landscape of multiple myeloma pathogenesis—...

Mo1272 CIRCULAR RNA CDR1AS DESTABILIZES MRNAS ENCODING TIGHT JUNCTIONS VIA INTERACTION WITH MIR-7 RESULTING IN INTESTINA...

Surprise RNA Discovery Challenges Long-Held Beliefs About How Genes Work

Scientists have identified a new RNA molecule that may play a key role in improving survival in cancer patients. In a recent study published in the Proceedings of the National Acad...

Non-Coding RNAs: New Biomarkers, Therapies for NEC

Necrotizing enterocolitis (NEC), a devastating gastrointestinal disease primarily affecting preterm infants, continues to challenge neonatal care with its high rates of morbidity a...

New RNA interaction atlas expands understanding of gene regulation

RNA sequencing and new computational tools enabled construction of a large RNA interactome atlas linking RNA-binding proteins, RNA interactions, and gene regulation...

CAMP4 Therapeutics preprints pioneering study on regulatory RNA profiling and gene upregulation

RNA sequencing with regRNA Capture-seq identified thousands of regulatory RNAs and enabled new strategies to increase expression of disease-related genes using ASOs...

Comment on “Ocrelizumab modulates the IL-2 signaling pathway and associated lncRNAs in multiple sclerosis”

Rangani et al. [1], present an exploratory investigation of IL-2 pathway gene and long non-coding RNA (lncRNA) expression in peripheral blood mononuclear cells (PBMCs) from untreat...