Search results for Interferon Response

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journals.plos.org /2 weeks ago

USP39 promotes antiviral defense through post-transcriptional control of RIG-I and stabilization of STING

by Jiazheng Quan, Xibao Zhao, Shaoying Chen, Hongrui Li, Wei Chen, Qianqian Di, Xunwei Li, Jiajing Zhao, Han Wu, Jin Chen, Yue Xiao, Zherui Wu, Weilin Chen RIG-I and STING are cri...

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journals.plos.org /1 month ago

Spatio–temporal modelling of <i>in vitro</i> influenza A virus infection: The impact of defective interferin...

by Yimei Li, Bjarke Frost Nielsen, Simon A. Levin, Aartjan J.W. te Velthuis, Bryan T. Grenfell Defective interfering particles (DIPs) are incomplete viral genomes that modulate in...

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jns-journal.com /1 month ago

No interferon-beta antibodies in natalizumab-treated multiple sclerosis patients with progressive multifocal leukoenceph...

Interferon beta therapy (IFN-β) can induce production of antibodies (NAbs) that may neutralize both therapeutic IFN-β and endogenous IFN-β, potentially impairing antiviral immunity...

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news-medical.net /1 week ago

Combination therapy improves response rates for chronic hepatitis B patients

The optimal management strategy for adults with immune-tolerant (IT) chronic hepatitis B infection remains undefined. This study aimed to investigate the efficacy and predictive fa...

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rna-seqblog.com /2 weeks ago

Small change in RNA, big impact on innate immunity

RNA sequencing and protein interaction analyses reveal how a single nucleotide at the start of RNA can alter antiviral immune signaling and influence therapeutic RNA design...

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journals.plos.org /1 week ago

Redundant and distinct mechanisms suppress innate immune activation during SARS-CoV-2 infection

by Fuchun Zhou, Sivakumar Periasamy, Nathaniel D. Jackson, Wan Sze Cheng, Ruben Soto Acosta, Aarti Tripathi, Kritika Kedarinath, Philipp A. Ilinykh, Chengjin Ye, Shailendra Chauhan...

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