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RNA sequencing data helped power an AI model that predicts gene regulation across cell types, improving the interpretation of genomic activity and supporting future precision medic...
Single-cell RNA sequencing identified an electromagnetic field-responsive gene, enabling researchers to develop a reversible switch for precise, non-invasive control of gene expres...
A new study has found that the signals cells use to switch genes on have remained almost unchanged across two billion years of evolution, but the ones used to switch genes off vary...
DNA regulatory elements, which control when, where, and to what extent specific genes are turned on or off, can be co-opted by scientists to create gene switches. The post Gene Sw...
by Carolyn Sangokoya, Isabella R. Rosso, Rana Ghandehari-Alavijeh, Robert Blelloch Post-transcriptional control by RNA binding proteins (RBPs) and microRNAs play central roles in...
Nearly every cell in the human body contains essentially the same genetic information, yet different cells activate different genes. For regulatory proteins to reach these genes, D...
Researchers at Dongguk University in South Korea have developed an electromagnetic-field-responsive gene switch that can activate and deactivate genes inside living animals with re...
by Jana Brunner, Anca Neagu, Dimos Gaidatzis, Lucas J. Morales Moya, Helge Großhans The RNA-binding protein (RBP) LIN28 is a key regulator of temporal cell fates, promoting stem c...
Our understanding of transcript elongation by metazoan RNA polymerase II (Pol II) has grown notably in recent years. Advances in structural biology have defined the interactions th...
DeepDETAILS combines artificial intelligence with RNA sequencing and chromatin data to reconstruct cell-specific gene regulation from bulk tissue sequencing experiments...
Avenue Biosciences´ machine learning-powered platform engineers and screens signal peptide variants to increase protein secretion from cells. Circio’s circVec technology has demons...
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