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In a groundbreaking advance poised to reshape gene therapy and molecular medicine, researchers have unveiled a novel strategy for precise gene regulation via RNA splicing modulatio...
by Hidetaka Katow, Thao Nguyen, Sarah Hyunsoh Park, Hyung Don Ryoo The Integrated Stress Response (ISR) mediates cellular adaptation to endoplasmic reticulum (ER) stress, amino ac...
While 3' UTRs have traditionally been dismissed as key regulators, a new study shows that these highly conserved mRNA tails facilitate the folding of intrinsically disordered prote...
In the intricate landscape of genetic regulation, the study of RNA-binding proteins is unraveling new dimensions of molecular control mechanisms pivotal for development and disease...
Deep learning unveils how drugs affect the dynamics of key structures within the cell. A new study maps condensate morphology to functional outcomes and sheds light on markers of h...
RNA sequencing with regRNA Capture-seq identified thousands of regulatory RNAs and enabled new strategies to increase expression of disease-related genes using ASOs...
Typically, the information encoded in DNA allows organisms to develop, function, and pass traits across generations. Yet DNA alone does not explain how genes are switched on and of...
A new CRISPR method can precisely boost rRNA production, allowing researchers to control protein production in cells and study disease mechanisms.
by Debomita Chakraborty, Raghunathan Rengaswamy, Karthik Raman A unique balance of seemingly contradictory properties like robustness and plasticity, or evolvability and functiona...
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