Latest updates for Differential Gene Expression

Fresh curated links around differential gene expression are collected here so marketers can spot useful updates and turn timely ideas into posts faster.

Recent items include:

  • The Lomb–Scargle periodogram-based differentially expressed gene detection along pseudotime
  • Asymmetry in the evolution of the male and female germlines
  • Evolutionarily Diverse Organisms Switch Genes on Simply and Switch Them off Dynamically

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Fresh articles and ideas

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rna-seqblog.com /1 month ago

The Lomb–Scargle periodogram-based differentially expressed gene detection along pseudotime

RNA sequencing combined with a new computational method improved detection of genes that change during cellular transitions, helping researchers better understand...

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journals.plos.org /1 month ago

Asymmetry in the evolution of the male and female germlines

by Carina F. Mugal, Marie Sémon A new study in PLOS Biology shows that in Drosophila, patterns of molecular evolution differ between genes expressed during oogenesis and spermatog...

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genengnews.com /1 month ago

Evolutionarily Diverse Organisms Switch Genes on Simply and Switch Them off Dynamically

A new study has found that the signals cells use to switch genes on have remained almost unchanged across two billion years of evolution, but the ones used to switch genes off vary...

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journals.plos.org /1 month ago

Meis1 isoform diversity orchestrates neural progenitor differentiation by regulating ATOH1 degradation at distinct subce...

by Tomoo Owa, Toma Adachi, Ryo Shiraishi, Kentaro Ichijo, Kaiyuan Ji, Minami Mizuno, Kyoka Suyama, Kayo Nishitani, Ikuko Hasegawa, Masaki Sone, Daisuke Kawauchi, Tomoki Nishioka, S...

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rna-seqblog.com /3 weeks ago

Novel electromagnetically tunable gene switch enables precise control of gene expression

Single-cell RNA sequencing identified an electromagnetic field-responsive gene, enabling researchers to develop a reversible switch for precise, non-invasive control of gene expres...

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journals.plos.org /1 month ago

Comparative single-nucleus transcriptomics reveals asymmetric evolution of the <i>Drosophila</i> male and fe...

by Imtiyaz E. Hariyani, Sudeshna Das, Emma M. Le, Carmen Gamero-Castano, Tina Soroudi, Joshua Choi, Spring Momeni, Justin C. Kim, Rongying Lu, Vivek Swarup, José M. Ranz Reproduct...

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rna-seqblog.com /1 week ago

scLS – a computationally efficient differentially expressed gene detection algorithm

A new RNA sequencing analysis method uses the Lomb-Scargle periodogram to efficiently identify genes associated with pseudotime across complex single-cell trajectories...

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journals.plos.org /2 weeks ago

Metabolic and developmental rate divergence between serially homologous cells underlies an evolutionary innovation in &l...

by Ben R. Hopkins, Olga Barmina, Xinying Wang, Mandy M. Situ, Haley A. Bolanos, Shizhan Nie, Artyom Kopp The individualization of serially repeated homologs is one route through w...

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journals.plos.org /1 month ago

Assessing scale and predictive diversity in models for single-cell transcriptomics based on Geneformer

by Junfan Chen, Fabian Schmidt, Ricardo Henao Single-cell transcriptomic data provide critical insights into cellular states and disease mechanisms, and foundation models have rec...

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rna-seqblog.com /1 month ago

DeepDETAILS – high-resolution reconstruction of cell-type-specific transcriptional regulatory processes from bulk sequen...

DeepDETAILS combines artificial intelligence with RNA sequencing and chromatin data to reconstruct cell-specific gene regulation from bulk tissue sequencing experiments...

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journals.plos.org /1 week ago

Post-transcriptional regulation of Profilin-2 by microRNAs and RNA-binding proteins forms a critical regulatory node for...

by Carolyn Sangokoya, Isabella R. Rosso, Rana Ghandehari-Alavijeh, Robert Blelloch Post-transcriptional control by RNA binding proteins (RBPs) and microRNAs play central roles in...

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bioengineer.org /2 weeks ago

ID2 directs cDC1 development by blocking E proteins at versatile Zeb2 enhancer

A new study has uncovered how the immune system locks developing cells into the type 1 classical dendritic cell, or cDC1, lineage—an immune cell population that plays a central rol...

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genengnews.com /1 month ago

Gene Therapy Partners Aim to Enhance Protein Expression

Avenue Biosciences´ machine learning-powered platform engineers and screens signal peptide variants to increase protein secretion from cells. Circio’s circVec technology has demons...

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rna-seqblog.com /2 weeks ago

A functionally integrated cross-tissue alternative splicing program during short-term calorie restriction

RNA sequencing reveals that calorie restriction drives dose-responsive alternative splicing across multiple tissues, affecting mitochondrial, translational, and RNA quality-control...

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webwire.com /2 days ago

New method allows scientists to follow gene activity over time in the same cells

The following press release was issued by the Broad Institute of MIT and Harvard. - - In recent years, scientists have built methods to measure a cell's transcriptome, or all t...

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journals.plos.org /4 weeks ago

Social isolation upregulates <i>takeout</i> expression in female <i>Drosophila melanogaster</i>...

by Elisabeth A. Tawa, Lisa Schneper, Katherine I. Cho, Mindy Sim, Eve Schoeffler, Daniel A. Notterman Previous research suggests that social isolation induces changes in gene expr...

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journals.plos.org /1 day ago

Not every gene is special: Modelling scale controls the false discovery rate when analysing high-throughput sequencing d...

by Scott J. Dos Santos, Andreea C. Murariu, Justin D. Silverman, Gregory B. Gloor Differential expression/abundance analyses are commonplace in studies employing high-throughput s...

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rna-seqblog.com /5 days ago

Single-cell and single-embryo RNA sequencing

Single-cell and single-embryo RNA sequencing enables detailed analysis of gene expression and cell identity during the earliest stages of embryonic development...

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