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We talked about effects of CD20 on CNS cells. The paper today helps support the view of the event in the brain as it relates to cladribine. It shows that cladribine is getting MS u...
This study uses high end technology to delve into the “unclear” and the conclusion is that cladribine gives long-term depletion of memory B cells and then we can say “Should have g...
Irradiation of cellular blood components prevents transfusion-associated graft-versus-host disease (TA-GVHD). An overview of what TA-GVHD is can be found on slides 3 & 4 of thi...
ProfK is a CladLad and has been flying the flag for many years. I put this paper up as it reinforces what I was saying about breaks after anti-CD20. Someone asked me if we will eve...
In addition to controlling multiple sclerosis (MS), the approved therapy Mavenclad (cladribine) may also help manage certain coexisting autoimmune diseases, potentially allowing so...
Liberate Bio’s investigational CAR-M cell therapy LIB820 may help successfully eliminate disease-driving B-cells in autoimmune diseases such as multiple sclerosis (MS) without caus...
FRIDAY, June 5, 2026 — An already available two-pill combo treats leukemia just as well as IV drugs, which should make cancer treatment easier on older adults, a new clinical tria...
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