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A comparative study in two beetle species links evolving regulatory DNA and condition-specific chromatin changes to horn diversification, with functional evidence for two BMP-pathw...
by Phillip L. Davidson, Isabel G. Manley, Armin P. Moczek Condition-responsive growth is a common feature of multicellular development, during which organisms integrate genetic an...
by Rafael Riudavets Puig, Denise G. O’Mahony, Ina Skaara Brorson, Ksenia Sokolova, Vessela N. Kristensen, Anthony Mathelier Transcription is regulated through the sequence-specifi...
by Ruiqi Yuan, Jianzhi Zhang In bacteria with circular chromosomes, genes near the replication origin (oriC) are replicated earlier and consequently attain higher copy numbers tha...
by Yi Qiu, Emilie Hebraud, Fanny Pouyet, Alexander F. Palazzo In the human genome, mutation rates vary along genes, yet how their fine-scale structure contributes to gene evolutio...
by Lu Chai, Jie Gao, Tinghe Guo, Teer Ba, Zihan Li, Junjie Liu, Yong Wang, Lirong Zhang CTCF is a key architectural protein with diverse roles in genome organization and gene regu...
by Carolyn Sangokoya, Isabella R. Rosso, Rana Ghandehari-Alavijeh, Robert Blelloch Post-transcriptional control by RNA binding proteins (RBPs) and microRNAs play central roles in...
A new PLOS Genetics study finds that bacterial gene positions along the chromosome show gradients in mean and growth-dependent expression consistent with selection shaped by replic...
Researchers developed CASREL, a machine learning framework that uses single-cell RNA sequencing to identify potential regulators of alternative splicing across different tissues an...
by Kazunori Ando, Sushant Bangru, John Welsby, John D. Thompson, Kenneth D. Poss Regeneration programs enable animals to restore damaged or lost tissues, and the range of stimuli...
RNA sequencing combined with AI helps Unify compare cell types across distant species by identifying shared biological functions even when individual genes no longer directly...
The Malik Lab thrives on competition. But for HHMI investigator Harmit Malik and his team at the Fred Hutchinson Cancer Center, it's the genomes—not the people—that are in conflict...
The junk DNA paradigm shift is a good example of how an intelligent design framework can serve as a productive guide to scientific research. Source
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