Search results for Cartilage Degeneration

NR0B2 is Protective of Cartilage, But Expression Decreases as Osteoarthritis Progresses

Cartilage is one of the least regenerative tissues in the body, and thus damage and aging leads to osteoarthritis, disability, and joint pain. There is considerable interest in fin...

Arg-1 Makes Macrophages More Inflammatory, Impairing Cartilage Regeneration with Age

Cartilage tissue exhibits a relatively poor capacity for regeneration even in youth, but this capacity for maintenance and repair diminishes with age. There are thus some gains to...

Regeneration, ReNu®, and the Race Against Knee OA

If your clinic schedule is anything like most, knee osteoarthritis (OA) isn’t just a diagnosis — it’s practically a recurring character.

New Treatment Could Reverse Osteoarthritis Within Weeks

Experimental osteoarthritis therapies repaired damaged joints in animals and may enter clinical trials within 18 months. A new experimental treatment may one day allow arthritic jo...

Comparative whole-genome analyses of articular chondrocytes and skin fibroblasts reveal distinct genome instability land...

by Safia Mahabub Sauty, Jacqueline Shine, Hamed Bostan, Jian-Liang Li, Piotr A. Mieczkowski, Richard F. Loeser, Brian O. Diekman, Dmitry A. Gordenin DNA damage lesions can result...

Beyond Pain Relief: Scientists Discover a Protein That Could Stop Osteoarthritis in Its Tracks

Researchers have identified the SHP protein as a key regulator that suppresses cartilage-degrading enzymes and slows osteoarthritis progression. For millions of people living with...

5 High-Collagen Foods That Help Regenerate Cartilage in Dogs

Cartilage breakdown in dogs can lead to stiffness, pain, and long-term joint problems. Supporting healthy cartilage through diet is one of the most effective ways to help your dog...

Scientists Test New Ways To Regrow Joints Damaged by Arthritis

TUESDAY, April 7, 2026 — Good news: Scientists may be closer to a new way to treat arthritis. The Advanced Research Projects Agency for Health (ARPA-H) said several experimental tr...

Uncovering the Cellular Secrets Behind Jaw Joint Arthritis Triggers

Temporomandibular joint osteoarthritis (TMJ-OA) represents a significant yet understudied facet of musculoskeletal degenerative diseases. Unlike osteoarthritis affecting larger joi...

More treatments expand personalized ankle cartilage repair

Historically, osteochondral lesions of the talus were treated with debridement with or without bone marrow stimulation techniques.However, data published in 2023 from Xiangyun Chen...

This Treatment Could Reverse Osteoarthritis Joint Damage With a Single Injection

Osteoarthritis has no cure, but researchers have developed new therapies that help aging or damaged joints repair themselves in a matter of weeks.

6 Ways to Support Cartilage Regeneration in Senior Dogs

As dogs get older, their joints can become stiff and painful due to cartilage breakdown. Cartilage doesn’t repair easily on its own, which is why senior dogs often need targeted su...

Osteoarthritis not just a ‘wear and tear’ disease

DESTIN, Fla. — Osteoarthritis, far from being “simply wear and tear,” demands a multifaceted management strategy, according to a speaker at the Congress of Clinical Rheumatology Ea...

Pain management of talar osteochondral lesion

Click here to read the Cover Story, “More treatments expand personalized ankle cartilage repair.”A middle-aged, active patient — the kind who alternates between running along the c...

Pain management of talar osteochondral lesion

Click here to read the Cover Story, “More treatments expand personalized ankle cartilage repair.”A middle-aged, active patient — the kind who alternates between running along the c...

Osteochondral defect 3rd metatarsal head

I saw 24 yrs old male last week with two year history of metatarsalgia, acute onset following dorsal/medial dislocation of 3rd metatarso-phalangeal joint during barefoot beach voll...

Piezoelectric MXene scaffold promotes cartilage repair while limiting vessel growth

An origami scaffold uses electrical repair cues and light-triggered heating to promote cartilage formation while limiting vessel growth beneath the defect.

A Common Knee Surgery Has Been Failing Decades, May Make Things Worse

Every year, surgeons trim millions of damaged knee cartilages in a procedure so routine that most patients spend fewer than 24 hours in hospital. The logic seems airtight: if your...

Morphological changes of the infrapatellar fat pad during squat in patients with patellofemoral cartilage lesions

Mechanical stress causes patellofemoral cartilage lesions. The role of the infrapatellar fat pad (IFP) is to adjust mechanical stress, and identifying changes to its morphology cou...

Glenohumeral Osteoarthritis: Pathophysiology, Diagnosis, and Arthroscopic Treatment

This article reviews glenohumeral osteoarthritis—its primary/secondary etiologies, clinical features, and imaging—and focuses on Comprehensive Arthroscopic Management (CAM) as a jo...

Quick Tip for More Viable OCA Grafts: ‘Be Cool’

New data for Smith+Nephew’s CARTIHEAL◊ AGILI-C◊ Cartilage Repair Implant demonstrates superior pain relief and fun...

Smith+Nephew announced further compelling evidence from a multicenter RCT highlighting the clinical superiority of its CARTIHEAL AGILI-C Cartilage Repair Implant resulted in higher...

Differential Effects of Degenerative Spine Disease and Spinal Fusion on the Risk and Progression of Hip Osteoarthritis:...

The hip and lumbar spine function as an integrated biomechanical unit, and spinal pathology may influence hip joint loading. However, population-level evidence regarding whether lu...