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zootecnicainternational.com /3 weeks ago

Immune system and nutrition: the balance between immunity and growth in modern broiler crosses

Immune activation is the first stage of the immune response necessary to protect the body. It is accompanied by significant metabolic costs and inflammation. When immune cells are...

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bioengineer.org /1 week ago

Mitochondria Drive Immune Cell Activation and Boost Immunotherapy Effectiveness

In a groundbreaking study that unveils a crucial metabolic dimension in immune activation, researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identi...

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letlifehappen.com /1 month ago

Dana-Farber Research Uncovers Approach to Activating the Immune System Against Metastatic Breast Cancer

From: dana-farber.org Summary: Cancer spreads, or metastasizes, when tumor cells shed from a primary solid tumor, for example in the breast, and embed in other organs, such as the...

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news-medical.net /1 week ago

Polymer-based immunotherapies enhance tumor targeting and immune activation

Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less than 30% of patients.

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news-medical.net /1 month ago

Boosting mitochondrial function in dendritic cells can improve cancer immunotherapy

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - a...

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neurosciencenews.com /1 month ago

Single Immune Switch Drives Both Arthritis and Alzheimer’s

Researchers identify TREM-1 as a potent amplifier of the innate immune system. The review suggests that targeting this receptor could provide new treatments for sepsis, arthritis,...

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journals.plos.org /1 week ago

Mannose-binding lectin 2 secreted by hepatocellular carcinoma cells recruits and activates natural killer cells to resha...

by Hangyu Liao, Jun Yang, Lei Cai, Luhao Chi, Chunming Wang, Yuyan Xu, Juncheng Xie, Kunling Chen, Jingyuan Pei, Zesheng Jiang, Mingxin Pan, Liang Zhao Crosstalk between hepatocel...

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scienceblog.com /5 days ago

Your Mitochondria Are Running Your Immune System’s Surveillance Network

Inside a dendritic cell, something is being decided. The cell has just swallowed a fragment of debris from a dead tumour neighbour and is now, in a sense, reading it, translating m...

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journals.plos.org /1 month ago

Leveraging mathematical models to predict and control T-cell activation

by Xabier Rey Barreiro, Jose Faro, Alejandro F. Villaverde T-cell receptor (TCR)-mediated T-cell activation is a key process in adaptive immune responses. The complexity of this p...

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gastrojournal.org /4 weeks ago

Blockade of Tumor TAK1 Induces DNA Damage and Immunogenic cGAS–STING Pathway Activation in Pancreatic Cancer

Targeting the Transforming Growth Factor-β (TGF-β) pathway to reverse the immunologically “cold” tumor microenvironment (TME) of pancreatic ductal adenocarcinoma (PDAC) remains cli...

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news-medical.net /2 weeks ago

Researchers develop pH and redox-sensitive systems to reduce immunotherapy toxicity

Although cancer immunotherapy has transformed treatment by harnessing the immune system to eliminate tumors, only a small subset of patients benefit. Many solid tumors remain "cold...

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scitechdaily.com /1 month ago

Saunas May Do More Than Raise Body Temperature – They Activate Your Immune System

A brief sauna session may quietly mobilize the immune system. A sauna session may do more than raise your heart rate and body temperature. A new study from Finland found that it al...

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genengnews.com /4 weeks ago

DNA-Containing Extracellular Vesicles Boost Antitumor Responses in Mice

Preclinical studies showed that activated T cells secrete DNA-containing extracellular vesicles that enter other immune and tumor cells to stimulate immune responses, boosting T ce...

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kmbc.com /2 weeks ago

Small study hints that revving up immune cells might help fight HIV

Scientists are supercharging patients' own immune cells to try to fight HIV without today's drugs

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wlky.com /2 weeks ago

Small study hints that revving up immune cells might help fight HIV

Scientists are supercharging patients' own immune cells to try to fight HIV without today's drugs

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bioengineer.org /1 day ago

Key CAR-T Cell Traits Trigger Myeloid Activation

In a groundbreaking study that could redefine the landscape of cellular immunotherapy, researchers have delved deep into the molecular and cellular dynamics underpinning CAR-T cell...

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wcpo.com /2 weeks ago

Small study hints that revving up immune cells might help fight HIV

Scientists are tweaking a powerful cancer therapy in hopes it could fight HIV instead, by supercharging patients' own immune cells.

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genengnews.com /1 month ago

Immunotherapy Enhanced by Restoring Mitochondrial Function in Dendritic Cells

A new metabolic mechanism describes how tumors disable immune “gatekeeper” cells in the presence of cancer. Study shows that boosting mitochondrial function in dendritic cells enha...

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activistpost.com /3 weeks ago

Butyrate’s Impact on Your Immune System

Story at-a-glance Your body is an intricate and remarkably efficient system constantly working to maintain a state of balance and health. A crucial component of this complex networ...

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bioengineer.org /1 month ago

Reprogramming Key Immune ‘Gatekeeper’ Cell Could Enhance Cancer Immunotherapy

In a groundbreaking study published in the renowned journal Science, researchers at St. Jude Children’s Research Hospital have unveiled a critical mechanism by which tumors suppres...

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pubs.rsc.org /1 day ago

Integrating Molecular Dynamics Simulations to Enable Rational Assembly of Immune Signals for Immunotherapy

Nanoscale Horiz., 2026, Accepted ManuscriptDOI: 10.1039/D6NH00215C, Communication Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported L...

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fightaging.org /1 month ago

An Approach to Reduce Harmful Inflammation without Greatly Compromising the Normal Immune Response

Excessive, constant inflammation in response to aspects of one's own cellular biochemistry is a feature of both autoimmune disease and aging. While transient inflammation is necess...

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fightaging.org /2 weeks ago

Lipopolysaccharide Exposure Before Injury Improves Regeneration in Aged Skin

Researchers here report an surprising, interesting, but not immediately useful discovery relating to the interaction of the immune system with wound healing in aged skin. Regenerat...

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hospitalnews.com /1 month ago

Unleashing natural killer cells against cancer

Scientists have developed a strategy to boost the cancer-fighting power of natural killer (NK) cells, part of the immune system’s first line of defence. NK cells can detect and des...

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