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rna-seqblog.com /1 month ago

Single Cell Discoveries Acquires TATAA Biocenter to Create an End-to-End Precision Biology CRO

Single Cell Discoveries (SCD), a specialist contract research organization (CRO) focused on discovery transcriptomics, has completed the acquisition of TATAA Biocenter...

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aacr.org /1 month ago

Harmonizing Data Collection for Precision Oncology: AACR Project GENIE® Data Model

The AACR Project GENIE Data Model, recently released by the AACR GENIE consortium, is an open-access tool designed to help simplify data harmonization in precision oncology. Learn...

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journals.plos.org /1 month ago

Direct microhaplotype genotyping for GT-seq (Genotyping-in-Thousands by Sequencing) using a diploid abundance model

by Nathan R. Campbell, Amanda R. Campbell, Shannon K. Blair, Amanda J. Finger GT-seq (Genotyping-in-Thousands by Sequencing) is widely used for high-throughput amplicon genotyping...

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journals.plos.org /1 week ago

Genome-Wide DNA methylation profiling of tissue-plasma pairs identifies Novel cfDNA biomarkers for the diagnosis of gast...

by Hailing Ou, Jinli Miao, Fusheng Ling, Jie Gao, Tingan Wang, Zhihua Ye, Chunbo Zhang, Mingwei Huang, Yuzhou Qin Screening for gastric cancer (GC) is critical for improving patie...

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rna-seqblog.com /4 weeks ago

Single-cell TimeLapse-seq reveals MTA is an essential retrotransposon

Very early in development, an embryo must begin using its own genome instead of relying only on RNA and proteins inherited from the egg. This transition is known as zygotic genome...

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journals.plos.org /2 weeks ago

DeCTCF: Decoding CTCF binding sequences by leveraging predicted epigenomic features

by Lu Chai, Jie Gao, Tinghe Guo, Teer Ba, Zihan Li, Junjie Liu, Yong Wang, Lirong Zhang CTCF is a key architectural protein with diverse roles in genome organization and gene regu...

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journals.plos.org /2 weeks ago

Integrated multi-omics analysis reveals the molecular landscape and therapeutic strategies in Chinese cervical cancer pa...

by Tao Pan, Xucui Zhuang, Ya Zhang, Jiyu Guo, Si Li, Can Zhang, Lili Han, Fuxia Li, Yueying Gao, Jinyang Yu, Yongsheng Li, Chaoyang Sun Genomic or transcriptomic sequencing guides...

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genengnews.com /6 days ago

Designing the Ecosystem for CGT Success

This proceedings eBook, developed in partnership with GEN and Cincinnati Children’s Hospital Applied Gene and Cell Therapy Center, captures perspectives and lessons from The Cell S...

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journals.plos.org /2 weeks ago

A graph-attentive GAN for rare-cell-aware single-cell RNA-seq data generation

by Ritwik Ganguly, Sana Aafrine, Sk Md Mosaddek Hossain, Sumanta Ray A central challenge in downstream single-cell RNA sequencing (scRNA-seq) analysis is the high-dimensional, sma...

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journals.plos.org /16 hours ago

Multi-omics analysis of high-grade serous ovarian cancers reveals heterogeneity and distinct immunological patterns base...

by Jing Qian, Rania Bassiouni, Yuxin Jin, Seeta Rajpara, Monica Neuman, Varun U. Khetan, Bodour Salhia, David W. Craig, Joseph W. Carlson, Lynda D. Roman, John D. Carpten High-gra...

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rna-seqblog.com /1 week ago

GARAGE improves rare cell detection in single-cell RNA sequencing analysis using AI

GARAGE uses artificial intelligence to generate realistic single-cell RNA sequencing data, improving rare cell representation, gene selection and cell clustering in complex biologi...

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journals.plos.org /1 month ago

scGSI: Graph-guided self-supervised integration of paired single-cell multi-omics

by Xiang Chen, Zihan Yang, Xiaoyu Liu, Zhiyi Xie, Wenlu Guo Paired single-cell multi-omics technologies provide direct within-cell correspondence across molecular layers and offer...

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newswire.com /1 month ago

Join TransCode Therapeutics' Live Investor Webinar: Advancing a Multi-Platform Oncology Pipeline Targeting Metastatic Ca...

Learn how TransCode Therapeutics is advancing RNA therapeutics, cancer vaccines, and immuno-oncology programs designed to address advanced and metastatic cancersManagement to discu...

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journals.plos.org /1 month ago

Tcf15 promotes an open nucleolar chromatin state to safeguard ribosome biogenesis and genome stability in mouse embryoni...

by Yu-ping Dong, Yi-Min Chen, Min Tang, Hu Zhou, Lin Wang, Ping Zheng Embryonic stem cells (ESCs) exhibit a hyperactive chromatin state at ribosomal RNA (rRNA) genes, which not on...

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thehindu.com /1 month ago

Genome Analysis Centre to be established in Amaravati, says Health Minister

Satya Kumar Yadav inaugurates a genome sequencing centre at the NATCO cancer centre at the Government General Hospital in Guntur; says the proposed Quantum Valley centre will expan...

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bioengineer.org /2 weeks ago

New computational tool maps the cell-state crosstalk that decides survival in IDH-mutant glioma

A team at the National Cancer Institute has unveiled a computational framework that turns ordinary bulk tumor RNA-sequencing data into a map of the conversations between cell state...

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