The history of spatial transcriptomics at Sanger
At the Wellcome Sanger Institute, advances in spatial transcriptomics and RNA sequencing enable detailed mapping of gene expression and cellular interactions within complex tissues...
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At the Wellcome Sanger Institute, advances in spatial transcriptomics and RNA sequencing enable detailed mapping of gene expression and cellular interactions within complex tissues...
RNA sequencing combined with spatial profiling tracks gene expression and cell proliferation, revealing dynamic cellular interactions and uncovering new insights into development.....
RNA sequencing supports space biology research by enabling transcriptome-wide analysis of gene expression changes associated with spaceflight and adaptation to space environments.....
RNA sequencing with NTVE enables repeated monitoring of gene expression in living cells, supporting time-course analysis of differentiation, perturbation responses, and cellular dy...
Takara Bio’s Trekker FX spatial transcriptomics improves single-cell resolution and detects more cell interactions, enhancing analysis of tumor microenvironments in cancer samples....
RNA sequencing using reference-free analysis uncovers novel transcripts and hidden gene features, expanding discovery beyond traditional genome-based approaches...
RNA sequencing reveals how transposable elements drive alternative splicing and alter translation in glioblastoma, generating diverse RNA isoforms linked to cancer progression...
RNA sequencing combined with spatial transcriptomics maps gene activity in the healthy human liver, revealing zonation patterns and early cellular changes linked to steatosis
TAP-seq combines genome editing with targeted RNA sequencing to enable sensitive and cost-effective single-cell functional genomics screens...
RNA sequencing captures both coding and noncoding RNAs at single-cell resolution, revealing complex regulatory programs and cellular identities across development and disease...
Long-read RNA sequencing improves rare disease diagnosis by resolving transcript isoforms and variant effects, enabling more accurate interpretation of pathogenic splicing...
Advanced RNA sequencing methods, including IRISeq and EnrichSci, uncover spatial interactions and molecular changes linked to aging in vulnerable brain cell populations...
RNA sequencing with SCOTCH improves isoform-level analysis from long-read single-cell data, helping reveal cell-type-specific transcript diversity and novel RNA isoforms
CIPHER‑seq is a single‑cell method that measures RNA and proteins simultaneously, exposing gaps in cytokine signaling and reducing mitochondrial stress signatures to give a clearer...
RNA sequencing of newly synthesized transcripts reveals dynamic immune cell activation and gene regulation during infection, providing real-time insight into how immune responses a...
RNA sequencing enables precise mapping of RNA binding protein targets, improving detection of low-abundance interactions and advancing understanding of gene regulation...
by Nicholas J. Bradley, Sriram Pendyala, Katie Partington, Douglas M. Fowler Fluorescent in situ sequencing involves imaging-based sequencing by synthesis in intact cells or tissu...
Parse Biosciences enables RNA sequencing of FFPE samples at single cell resolution, unlocking archived tissues for whole transcriptome analysis and deeper insights into gene...
RNA sequencing from more than 22 million cells trained a model that predicts cell-type-specific gene expression and noncoding variant...
By developing IRISeq and EnrichSci, researchers can now map the spatial neighborhoods of millions of aging brain cells and zoom in on rare, vulnerable populations. Their discovery...
This Parse Biosciences and bit.bio alliance combines single-cell RNA sequencing and causal transcriptomics to map transcription factor-driven cell identity, enabling improved disea...
RNA sequencing with nanopore technology improves m6A modification mapping when paired with calibrated workflows, helping reveal cell-specific RNA regulation in fibroblasts and neur...
Every few minutes, a living cell does something quietly extraordinary: it sheds tiny membrane bubbles into the fluid around it. These extracellular vesicles carry molecular cargo (...
RNA sequencing combined with protein analysis enables detailed tracking of immune cell activity, revealing cytokine dynamics and improving understanding of cancer and immune respon...
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