Search results for Rna Therapeutics

Small change in RNA, big impact on innate immunity

RNA sequencing and protein interaction analyses reveal how a single nucleotide at the start of RNA can alter antiviral immune signaling and influence therapeutic RNA design...

CAMP4 Therapeutics preprints pioneering study on regulatory RNA profiling and gene upregulation

RNA sequencing with regRNA Capture-seq identified thousands of regulatory RNAs and enabled new strategies to increase expression of disease-related genes using ASOs...

DNA‑Guided CRISPR Suggests a New Direction for RNA Editing

The platform, called ΨDNA, reprograms Cas12 nucleases to recognize and act on RNA using a DNA-based guide scaffold. In human cell lines, ΨDNA achieved 70–95% knockdown of endogenou...

Wacker Expands Service Offerings with Launch of Contract Research for Nucleic Acid-Based Therapies

In addition to producing pDNA, RNA, and LNP formulations, Wacker’s CRS team offers construct design services, including plasmid and RNA construct design as well as RNA engineering...

Systematic assessment of diverse RNA modifications using nanopore direct RNA sequencing

RNA sequencing with nanopore technology reveals how diverse therapeutic RNA modifications affect signal detection, helping define current capabilities and limitations for modificat...

Programmable artificial RNA condensates in mammalian cells

Nature Nanotechnology, Published online: 29 April 2026; doi:10.1038/s41565-026-02164-7Modular RNA nanostar motifs spontaneously assemble into programmable synthetic condensates in...

Madrigal Pharma Adds Another Genetic Medicine to Its Drug Combo Strategy in MASH

Madrigal Pharmaceuticals has licensed rights to an Arrowhead Pharmaceuticals small-interfering RNA therapy designed to address a particular genetic mutation associated with the fat...

Oxford Nanopore and Lonza Launch Direct RNA Sequencing Solution for GMP mRNA Quality Control

RNA sequencing combined with nanopore technology and machine learning may streamline GMP quality control testing for mRNA therapeutics within a single workflow...

CRISPR-Based System Targets RNA and Kills Cells on Demand

Scientists have devised a CRISPR-based tool that can kill cells carrying a specific strand of RNA. The tested targets include cancerous and virus-infected cells [1]. Targeted assas...

Programmable RNA nanostars create custom artificial organelles inside cells

A new RNA-based method creates programmable artificial organelles inside living cells, enabling customizable compartments for nanomedicine and gene engineering.

Altamira Therapeutics Announces Publication Highlighting Potential of RNA Nanoparticles for Disease-Modifying Treatment...

Antisense oligonucleotide strategy reverses HNRNPH2-related neurodevelopmental disorder

Scientists at St. Jude Children's Research Hospital have found that they can reverse the effects of HNRNPH2-related neurodevelopmental disorder using antisense oligonucleotides (AS...

RNA Origami and Nanopores Accurately Size ALS Genes

A new study introduces an innovative platform capable of accurately sizing the toxic repeat expansion mutations that drive muscular dystrophy, Huntington’s disease, and ALS.

Bostongene RNA transcriptome profiling reveals new ADC targets in advanced solid tumor

RNA sequencing combined with multiomic analysis uncovers new therapeutic targets in advanced cancers, enabling identification of antibody drug conjugate options when DNA testing al...

RNA Horizons – Sept 16-18, 2026 – Munich, Germany

RNA Horizons 2026 will highlight advances in RNA therapeutics, biomarker discovery, and delivery technologies, bringing together experts to explore innovation across cancer, rare d...

Programmable RNA detection enables multiplex virus identification

RNA sequencing advances support CRISPR-based detection methods that use kinetic signatures to identify multiple viruses and variants from RNA in a single, rapid diagnostic assay...

Programmable RNA Targeting via DNA-Guided CRISPR-Cas12a

In a landmark advancement that could redefine molecular diagnostics, researchers have unveiled a groundbreaking DNA-guided CRISPR–Cas12a system capable of programmable RNA recognit...

Intellia races in vivo CRISPR therapy to FDA after phase 3 data paint ‘compelling’ picture

A phase 3 trial of Intellia Therapeutics’ in vivo gene editing therapy lonvoguran ziclumeran has hit its primary endpoint, leading the biotech to start a rolling submission for FDA...

A*STAR scientists develop new method to reveal how RNA structure influences health and disease

RNA sequencing with the new sm-PORE-cupine method reveals how individual RNA molecules fold and behave, offering insights into gene regulation, viral biology, and therapeutic disco...

Advances and Strategies in Antibody-Oligonucleotide Conjugates

In the swiftly evolving landscape of gene therapy, antibody-oligonucleotide conjugates (AOCs) have emerged as a transformative platform primed to revolutionize targeted molecular d...

Wobble Genomics to present novel mRNA sequencing research at AACR 2026

RNA sequencing of full-length mRNA from blood supports liquid biopsy approaches for selecting antibody-drug conjugate therapies in breast cancer, improving precision treatment deci...

ParcelBio Unveils Programmable mRNA Platform Backed by $13M Financing

Biotech startup ParcelBio is using newly secured financing to advance its mRNA platform and its therapeutic pipeline, which includes programs in autoimmune disease, oncology, and e...

WACKER offers Contract Research Services (CRS) for nucleic acid-based pharmaceuticals

- - • The new CRS expand WACKER's offering for biotech and biopharmaceutical customers worldwide and complement Wacker Biotech's CDMO services. - - • The Munich team at the...

Modular design of dual-targeted, enzyme-responsive peptide carriers for gene drug delivery

Nanoscale Horiz., 2026, Accepted ManuscriptDOI: 10.1039/D5NH00803D, CommunicationXinhao Jiao, Mingshan Han, Zixuan Wang, Jie Min, Rongxin Su, Hang Tie, Wei Qi, Yuefei WangGene-base...