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RNA Variant Imaging is attracting attention because it addresses a persistent blind spot in cancer diagnostics: many clinically relevant RNA isoforms, splice events, and fusion tra...
Researchers used Raman spectroscopy to distinguish 20 SARS-CoV-2 variants through RNA structural fingerprints, demonstrating a potential faster alternative to RNA sequencing...
Kite Pharma has developed a flow virometry technique to analyze single lentiviral particles, which they hope will improve product consistency by characterizing viral vector size an...
In a development that could reshape how nuclear cardiology is practiced worldwide, researchers in Japan have shown that a type of artificial intelligence called a variational autoe...
by Jiayu Zhang, Yiran Tao, Yun Zhao, Miaomiao Lei, Yucheng Shen, Qicong Li, Chenxu Liu, Jiuyuan Bai Visualizing the spatiotemporal dynamics of native RNA molecules with single-tra...
Researchers showed how optical metabolic imaging (OMI) can be used to characterize metabolic activity within immune cells from the peripheral blood of patients, which could potenti...
Live-cell RNA sequencing uses engineered virus-like particles to repeatedly sample transcriptomes without destroying cells, enabling researchers to track gene expression changes ov...
Illumina introduces SpliceAI2, an AI model that improves disease-relevant splice variant prediction, using genomic and RNA sequencing data to demonstrate greater accuracy in identi...
ResolVI improves spatial RNA sequencing analysis by correcting RNA assignment errors and technical variation, helping researchers distinguish cell states and detect subtle gene exp...
by Dee Velazquez, Caleb Hallinan, Roujin An, Kalen Clifton, Jean Fan Imaging-based spatially resolved transcriptomics (imSRT) technologies provide high-throughput molecular-resolu...
by Michael J. Murphy, Steven Mazur, Elena N. Postnikova, Brett P. Eaton, Gregory A. Kocher, Winston Chu, Matthew G. Lackemeyer, Syed Qasim Gilani, Jens H. Kuhn, Michael R. Holbrook...
RNA sequencing can read Detectron-generated DNA barcodes, enabling scalable detection of specific RNA signals associated with infection, gene activity and other cellular processes....
Adding a viral protein, NoV B2, helped self-amplifying RNA overcome cellular defenses and produce more target protein without diminishing immune stimulation, potentially enabling f...
RNA sequencing identified the novel tick-borne ALTNV in febrile patients in China, helping distinguish infections that can resemble Dabie bandavirus disease...
A new review maps how microRNAs, long non-coding RNAs and circular RNAs regulate the biological processes driving abdominal aortic aneurysm and could serve as future biomarkers and...
RNA sequencing identifies urinary miRNA signatures associated with bacterial and viral infections in children, supporting development of non-invasive biomarkers for distinguishing...
An analysis of more than 60,000 respiratory syncytial virus (RSV) sequences from around the world found that viral variants associated with resistance to current RSV prevention too...
RNA sequencing of urine cell-free RNA can detect bladder cancer, monitor residual disease and help predict whether patients may respond better to immunotherapy or chemotherapy...
RNA sequencing with eSTRAND RNA QC enables simultaneous measurement of RNA identity, poly(A) tail length, capping efficiency, fragmentation hotspots, and dsRNA...
High-speed atomic force microscopy reveals how antibodies bind to cancer-related proteins on individual extracellular vesicles, exposing differences in accessibility that conventio...
First clinical evidence demonstrating that a systemically delivered small activating RNA (saRNA) can safely upregulate an endogenous target protein in human skeletal muscle in a mo...
Cancer’s genetic chaos may soon be readable in the ordinary stained images pathologists already examine under a microscope. A new study published in Nature Biomedical Engineering i...
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