Social Media Ideas for Pathway Analysis

scFlowReport brings multiple single-cell RNA sequencing analyses into one workflow

RNA sequencing analysis with scFlowReport integrates differential expression, pathway enrichment, regulatory networks and cell communication into a reproducible workflow for compar...

Glycan reachability analysis: A bottleneck-aware framework for inferring tissue-specific glycan biosynthetic potential f...

by Yusuke Matsui Glycan biosynthesis requires the coordinated expression of glycosyltransferases, modifying enzymes, and nucleotide-sugar synthesis and transport machinery. Existi...

RNAmel simplifies RNA sequencing data analysis with a reproducible, integrated platform

RNAmel integrates RNA sequencing data analysis, gene expression profiling, pathway enrichment and visualization into a reproducible platform that simplifies...

GP-DHT uses single-cell RNA sequencing to map gene regulatory networks

Single-cell RNA sequencing combined with GP-DHT helps predict transcription factor and target gene relationships, providing a...

Genome-Wide Analysis Identifies BACH2 as Potential Fetal Hemoglobin Activation Target

This pathway, which the authors dub the “BACH2-NRF2 axis,” is independent of the well-known BCL11A transcription regulator, the target of the approved cell therapy Casgevy for sick...

Interpretable neural networks prioritize cancer driver genes from genome-wide dependency landscapes

by Qingyang Yin, Liang Chen Identifying cancer driver genes and their therapeutic impact remains a core challenge in computational cancer biology. We introduce xNNDriver and xAEDr...

FM-GPT: Bayesian fine mapping for phenome-wide transcriptome-wide association studies

by Travis Canida, Zhenyao Ye, Shao-Hsuan Wang, Hsin-Hsiung Huang, Yezhi Pan, Menglu Liang, Shuo Chen, Tianzhou Ma Transcriptome-wide association studies (TWAS) integrate genome wi...

HiFIseek: Gene-specific enrichment of high-impact mutations in associated genomic regions

by Rafael Riudavets Puig, Denise G. O’Mahony, Ina Skaara Brorson, Ksenia Sokolova, Vessela N. Kristensen, Anthony Mathelier Transcription is regulated through the sequence-specifi...

Analysis of multicellular anatomical structures from spatial omics data using sosta

by Samuel Gunz, Helena L. Crowell, Mark D. Robinson Spatial omics technologies enable high-resolution, large-scale quantification of molecular features while preserving the spatia...

Dynamic Landscape Analysis of cell fate decisions provides predictive models of neural development from single-cell data

by Marine Fontaine, M. Joaquina Delás, Meritxell Sáez, Rory J. Maizels, Elizabeth Finnie, James Briscoe, David A. Rand Building a mechanistic understanding of cell fate decisions...

Bulk RNA-seq Analysis: A Complete Beginner’s Guide

Bulk RNA sequencing helps researchers identify gene expression patterns associated with differences in drug response, supporting biomarker discovery and personalized medicine while...

Immune Pathway Contributing to Radiation Therapy-Related Lung Damage Identified in Mice

Working with a mouse model of radiation-induced lung injury, researchers uncovered an immune pathway that may contribute to radiation-related lung damage and, suggest their results...

UiPath, Inc. (PATH) Analyst/Investor Day - Slideshow

Systematic multivariate analysis of chromatin complex dependencies reveals Set1C/COMPASS as a melanoma-enriched epigenet...

by Luisa Quesada Camacho, Mohammad Fallahi-Sichani Epigenetic dysregulation is a common feature of cancer. It creates vulnerabilities arising from an increased reliance on chromat...