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By Lars Arendt-Nielsen Pain is one of the few things all of us experience, from stubbing a toe to waking up with an aching back; we can all relate to the feeling of being in pain.A...
A new project is investigating whether tiny stem-cell-derived particles can treat intractable neuropathic pain.
In “failing” this study delivered an important pain management insight for total hip arthroplasty surgeons…
A new study demonstrates that tracking high-speed facial micromovement spikes provides an objective, quantifiable metric for human discomfort.
In “failing” this study delivered an important pain management insight for total hip arthroplasty surgeons…
Summary: Researchers mapped the precise brain pathway that drives the nocebo effect, the biological phenomenon where negative expectations actively amplify physical pain. The resea...
By Jan VollertIn 2006, Carl Koch sued his employer for damages after burn injuries during a workplace accident left him with chronic pain. The employer accused him of malingering,...
A single dose of psilocybin provides up to a month of nerve pain relief and fundamentally supercharges the efficacy of traditional painkillers.
By Chris SeenanIn a 2026 study I conducted with colleagues on people with peripheral arterial disease, one participant described how leg pain had disrupted his golf for years. It f...
By Pat Anson A new study has found what many chronic pain patients have already learned the hard way: It’s difficult to get a diagnosis.Researchers at The University of Texas at Ar...
In a groundbreaking clinical development set to reshape the landscape of pain management, a recent phase I trial has unveiled the safety profile, pharmacokinetics, and pharmacodyna...
Three randomized controlled trials plus three case series — all looking at peripheral nerve stimulation as
In a significant stride toward unraveling the complex interrelations between physical discomfort and cognitive decline, a recent study sheds light on the often-overlooked connectio...
Local Anesthetic Injection Resolves Movement Pain, Motor Dysfunction, and Pain Catastrophizing in Individuals With Chronic Achilles Tendinopathy, a Non-Randomized Clinical Trial Jo...
A new study isolates the exact molecular mechanisms by which the viral protein glycoprotein 120 (gp120) intensifies neuropathic suffering.
By Dr. Forest Tennant and Ingrid HollisIn 1981, some neuroscience researchers discovered a group of hormones being made in the brain and spinal cord. Some are also made in the gon...
Is your pain a threat signal or tissue damage? Taylor Kruse breaks down the neuroscience of pain, stress and how it impacts training for runners. The post The Neuroscience of Pain:...
A new study introduces an artificial intelligence framework that analyzes EEG signals to objectively classify pain intensity.
Stimulated by Chen et al 2026.[1] EA – electroacupuncturePHN – postherpetic neuralgiaIF – impact factorNRS – numerical rating scaleSD – standard deviationMCID – minimum clinically...
By Crystal LindellOne of the strangest things about developing a chronic illness was realizing just how many people would suggest prayer to me as a medical treatment. They would sa...
“Women are now told if you take a couple of ibuprofen, you are fine with the pain. In reality, that is unlikely to be true,” says Professor Ben Mol, professor of Obstetrics and Gyn...
By Pat AnsonSome pain sufferers firmly believe that cannabis can help boost the pain relieving effects of prescription opioids. The evidence behind that belief is mostly anecdotal,...
By Pat AnsonScientists in Abu Dhabi have developed a tiny neuromodulation device that can treat chronic nerve pain without the need for invasive surgery. The experimental device is...
A novel neurotrophin-3 inhibitor significantly reduced pain and improved function vs. placebo for patients with knee osteoarthritis, according to results presented at the Osteoarth...
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