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genengnews.com /3 days ago

ASHG: Long-Read Genomics Meets Clinical Data in PacBio, Verily Health AI Deal

A multi-year collaboration will connect PacBio's HiFi sequencing with Verily Pre, combining long-read genomic and clinical data for biomedical research and AI model development. Th...

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rna-seqblog.com /2 weeks ago

PacBio and TychoBio Collaborate to Train AI Models for Rare Disease

PacBio Kinnex sequencing will generate full-length transcript data to help advance TychoBio’s drug discovery models PacBio, developer of the world’s most advanced sequencing techno...

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journals.plos.org /1 month ago

Direct microhaplotype genotyping for GT-seq (Genotyping-in-Thousands by Sequencing) using a diploid abundance model

by Nathan R. Campbell, Amanda R. Campbell, Shannon K. Blair, Amanda J. Finger GT-seq (Genotyping-in-Thousands by Sequencing) is widely used for high-throughput amplicon genotyping...

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bioengineer.org /2 weeks ago

Shrubby Cinquefoil Mitochondrial Genomes Reveal Hidden DNA Traffic Between Cell Compartments

The first complete mitochondrial genomes of Dasiphora fruticosa and D. glabra reveal stable gene cores, lineage-specific repeats, and extensive DNA transfer between cellular compar...

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genengnews.com /2 weeks ago

Expanding the Possibilities of Next-Generation Sequencing

Sequencing by expansion (SBX) and Roche’s AXELIOS 1 platform introduce a new approach to single-molecule sequencing, designed to give researchers flexibility across sequencing work...

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journals.plos.org /1 month ago

Hunting for microsatellite instability in long-read data with Owl

by Zev Kronenberg, Byunggil Yoo, Khi Pin Chua, Mark J. P. Chaisson, Lisa Lansdon, William J. Rowell, Guilherme de Sena Brandine, Jocelyne Bruand, Egor Dolzhenko, Kobe Ikegami, Jay...

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journals.plos.org /1 month ago

PanDelos-plus: A parallel algorithm for computing sequence homology in pangenomic analysis

by Simone Colli, Emiliano Maresi, Vincenzo Bonnici The identification of homologous gene families across multiple genomes is a central task in bacterial pangenomics traditionally...

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journals.plos.org /1 week ago

DipSkmer: Reference-free population genomics with diploid genome skims

by Eduardo Charvel, Homère J. Alves Monteiro, Siavash Mirarab, Vineet Bafna Ecologists and conservation biologists rely on genetic diversity as a key essential biodiversity variab...

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journals.plos.org /2 weeks ago

HiFIseek: Gene-specific enrichment of high-impact mutations in associated genomic regions

by Rafael Riudavets Puig, Denise G. O’Mahony, Ina Skaara Brorson, Ksenia Sokolova, Vessela N. Kristensen, Anthony Mathelier Transcription is regulated through the sequence-specifi...

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journals.plos.org /1 month ago

Characterization of METTL3/14-mediated m<sup>6</sup>A modification in human transcriptome using Nanopore dir...

by Emily Kurtyan, Andrew J. Stein, Kelly J. Abdalla, Zhangerjiao Yuan, Miten Jain, Fadia Ibrahim Post-transcriptional RNA modifications modulate diverse aspects of RNA metabolism....

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rna-seqblog.com /4 weeks ago

Eclipsebio expands its RNA characterization capabilities with multi-attribute nanopore-based sequencing assay eSTRAND RN...

RNA sequencing with eSTRAND RNA QC enables simultaneous measurement of RNA identity, poly(A) tail length, capping efficiency, fragmentation hotspots, and dsRNA...

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