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Some evidence suggests that deubiquitylases are relevant to aging. These enzymes remove ubiquitin from proteins; recall that the decoration of a protein with ubiquitin enables it t...
In a groundbreaking study that promises to revolutionize our understanding of renal health, researchers have unveiled a novel kidney-protective mechanism mediated by the reduction...
Researchers have outlined a key receptor and protein involved in the formation of cataracts, paving the way for potential treatments targeting them. […]
In a groundbreaking study poised to reshape our understanding of neurodegenerative diseases, researchers have unveiled a compelling link between metabolic stress and the worsening...
Low density lipoprotein (LDL) particles are a class of cholesterol transporter, carrying cholesterol out from the liver where it is manufactured to the rest of the body via the blo...
Cells have evolved responses to stress that enhance the chance of survival. Many of these responses converge of increased activity of maintenance processes, more recycling of mater...
In the heart of West Bengal, a silent environmental crisis is unfolding along the banks of the Churni River, a waterway long cherished by local communities for sustenance and daily...
A recent study described a process called ferro-aging, in which iron accumulation leads to oxidative damage and cellular senescence. This process can be delayed by Vitamin C [1]. A...
Not your average antioxidant
The integrated stress response in cells acts to reduce protein synthesis while enhancing maintenance activities. A number of sensors for different forms of cell stress all converge...
Proteostasis, or protein homeostasis, is a fundamental biological process ensuring that the vast array of proteins within a cell are accurately synthesized, properly folded, and ef...
Researchers here identify a common mechanism in the cellular responses to various forms of stress that appears to drive aspects of hematopoietic stem cell aging via impairment of m...
Diabetic ferroptosis plays an important role in triggering on inflammation in diabetic wound Shuangwen Li, Yuan Li, Ziyu Wu, Zhongming Wu*, and Hongjuan Fang 23 AUG 2021...
Cancer cells may be exploiting a common antioxidant as fuel, revealing a potential weakness that future therapies could target. Cancer cells may be tapping into an unexpected energ...
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