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Advances in end-to-end multiomics platforms and the underlying scientific knowledge now enable faster and more precise biomarker discovery, mechanistic insight generation, and ther...
Machine learning techniques can be used to generate aging clocks from any sufficiently complex set of biological data obtained from individuals of varying chronological ages. The r...
In an unprecedented stride toward deciphering the intricate web of human health, a comprehensive study combining whole genome sequencing and plasma metabolomics has unveiled geneti...
RNA sequencing joins genomic, proteomic, and clinical data in the expanded NIH All of Us database, creating an unprecedented resource for precision medicine research...
by Joshua M. Hess, Richard K. Dzeng, Iulian IlieЕџ, Denis Schapiro, John J. Iskra, Divya Mirgh, John Nam, Erin H. Seeley, David E. Verrill, Walid M. Abdelmoula, Michael S. Regan, G...
RNA sequencing delivers its greatest clinical value when multidisciplinary teams integrate laboratory, computational, and clinical expertise to ensure findings are accurate, interp...
by Joseph T. Benthal, Justin A. Avila, Jeffrey R. Smith, E. Michelle Southard-Smith Hirschsprung disease (HSCR) is characterized by absence of enteric ganglia (aganglionosis) alon...
by Tal Shay, Christophe O. Benoist, Ricardo Grieshaber-Bouyer High-throughput single-cell assays reveal data that defies discrete categorization. The ‘cell cloud’ model, grounded...
RNA sequencing supports space biology research by enabling transcriptome-wide analysis of gene expression changes associated with spaceflight and adaptation to space environments.....
by Jérôme Arnoux, Jean Mainguy, Laura Bry, Quentin Fernandez de Grado, Yazid Hoblos, David Vallenet, Alexandra Calteau Over the last decade, the expansion in the number of availab...
A groundbreaking study has revealed a surprising link between tyrosine kinase inhibitors (TKIs), widely used in cancer therapy, and the development of obesity. Scientists have unco...
by Pascal Lukas, Aurélien Gibeaud, Clarisse Schumer, Jonas Arruda, Jeremie Guedj, Olivier Terrier, Frederik Graw Understanding the mechanisms that govern viral spread in human air...
In a groundbreaking study poised to reshape our understanding of liver disease progression, researchers have illuminated a complex interplay between lipid mediators and mitochondri...
RNA sequencing and multi-omics profiling identified four molecular subtypes of high-risk bladder cancer, helping explain differences in immunotherapy response and recurrence risk.....
A multi-model AI framework improves cell type annotation accuracy for single-cell RNA sequencing data, helping researchers interpret complex cellular populations with greater.... T...
As the diversity of virtual cell models targets new dimensions of complex biology, every approach takes another step closer toward clinical impact. The post Virtual Cells Go Multis...
A groundbreaking study has unveiled new insights into the complex biology of cancer-associated fibroblasts (CAFs) within triple-negative breast cancer (TNBC), a particularly aggres...
MERCURIUSâ„¢ 1536 DRUG-seq brings RNA sequencing to large-scale compound screening, enabling efficient gene expression profiling... The post Alithea Genomics launches early access...
Scientists created an AI tool that can help to reveal how genes function together inside human cells dependent on the cellular context, which could ultimately help to support the d...
Next-generation MS platforms are transforming drug discovery by revealing complex biology earlier, faster, and at unprecedented depth. The post Mass Spectrometry’s Discovery Revolu...
by Mark Alber, Amber Smith, Reinhard Laubenbacher, Roeland M. H. Merks
STAMP combines imaging and RNA sequencing to link cell morphology with gene expression, enabling researchers to connect molecular profiles directly to observable cellular... The po...
Advances in RNA sequencing and spatial transcriptomics are revealing complex tumor ecosystems and enabling AI-driven approaches to improve precision immunotherapy and cancer treatm...
RNA sequencing combined with the ChiTaRS platform improves detection of disease associated chimeric RNAs, supporting biomarker discovery, liquid biopsy, and precision medicine...
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