AI tool maps hidden microRNA binding sites in circular RNA
A new AI-based tool identifies potential microRNA binding sites across circular RNA molecules, including regions conventional linear sequence analysis can miss, advancing research...
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A new AI-based tool identifies potential microRNA binding sites across circular RNA molecules, including regions conventional linear sequence analysis can miss, advancing research...
by Carolyn Sangokoya, Isabella R. Rosso, Rana Ghandehari-Alavijeh, Robert Blelloch Post-transcriptional control by RNA binding proteins (RBPs) and microRNAs play central roles in...
Deep learning applied to RNA sequencing analysis helps miRBind2 predict microRNA binding and gene repression directly from nucleotide sequence with improved accuracy..
Small RNA sequencing reveals cell-specific sdRNA patterns in AML and healthy hematopoiesis, linking certain snoRNA-derived RNAs to gene regulation and poorer patient outcomes...
Researchers report that the circular RNA circMTCL1, sharply depleted in colorectal cancer tumors, suppresses cancer cell growth by sponging miR-145-5p, boosting BMP3, and damping M...
Two naturally occurring microRNAs may help regulate the protein production that allows aggressive cancer cells to grow and divide.
A new review maps how microRNAs, long non-coding RNAs and circular RNAs regulate the biological processes driving abdominal aortic aneurysm and could serve as future biomarkers and...
That the calorie restriction imposed by GLP-1 receptor agonists induces loss of muscle mass has proved a boon for research into ways to address the loss of muscle mass that occurs...
Researchers publishing in Aging Cell have found that the regulatory protein MTR4 fights DNA damage in the blood vessel lining but decreases with aging. Vulnerable by nature […]
Direct RNA sequencing revealed thousands of chimeric mRNAs in mammalian cells, uncovering previously unknown proteins with roles in immunity, inflammation, and potential drug disco...
RNA Variant Imaging is attracting attention because it addresses a persistent blind spot in cancer diagnostics: many clinically relevant RNA isoforms, splice events, and fusion tra...
Researchers isolated exosome-like nanoparticles from the medicinal vine Paederia foetida and found they carry five anti-inflammatory terpenoids and 1,170 microRNAs predicted to tar...
RNA sequencing identifies urinary miRNA signatures associated with bacterial and viral infections in children, supporting development of non-invasive biomarkers for distinguishing...
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