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by Mark Alber, Marc R. Birtwistle, Stacey D. Finley, Pedro Mendes
by Elijah Gunther, Pablo G. Camara The three-dimensional structure of proteins is intimately linked to their function, yet establishing comprehensive frameworks for systematically...
Developing software to reveal large genetic changes that lead to cancer
Formulating software for the study of plant genomes
In a groundbreaking study published in Nature, researchers have unveiled a comprehensive genetic analysis illuminating the intricacies of branched-chain amino acid (BCAA) metabolis...
Creating techniques to allow scientists to see biological processes in real time
In a groundbreaking study poised to reshape the landscape of pancreatic cancer research, Chen, Lou, Guo, and colleagues have unveiled a sophisticated approach that links genetic mu...
Jill P. Mesirov, PhD, a luminary in the worlds of mathematics and computational biology, has embarked on a new chapter in her distinguished career by joining the Sanford Burnham Pr...
In a milestone moment for the field of molecular genetics, Alan G. Hinnebusch, PhD, a Distinguished Investigator at the National Institutes of Health, has been awarded the prestigi...
Marcia Marcia Marcia Anonymous (not verified) Mon, 05/18/2026 - 08:33 field_thread_url https://cafepharma.com/boards/threads/marcia-marcia-marcia.671172/...
Advances in end-to-end multiomics platforms and the underlying scientific knowledge now enable faster and more precise biomarker discovery, mechanistic insight generation, and ther...
by Holly A. Huber, Stacey D. Finley Computational models in systems biology are often underdetermined—that is, there is little data relative to the complexity and size of the mode...
by Arjun Singh, Ali I. Ukperaj, Gabriel F. Porto, Gregory L. Dignon Intrinsically disordered proteins (IDPs) exhibit phase separation behavior that is closely linked to their degr...
by Joseph T. Benthal, Justin A. Avila, Jeffrey R. Smith, E. Michelle Southard-Smith Hirschsprung disease (HSCR) is characterized by absence of enteric ganglia (aganglionosis) alon...
by Michael Zietz, Kathleen LaRow Brown, Undina Gisladottir, Nicholas P. Tatonetti Complex diseases are a major challenge, and genetics underlie a large fraction of the risk for th...
A new method screens large libraries of synthetic cyclic peptides to identify compounds that can enter cells for therapeutic effect, opening avenues for a modality that combines th...
Chromatography optimization should be considered not only in terms of quality, but also in terms of how each change affects processing time, congestion, and feasibility regarding s...
A new single-protein analysis technique gives researchers newfound ability to study scramblases, physiologically important proteins that translocate phospholipids bidirectionally a...
by Zhenhui He, Dong Kangning Resolving fine-grained cell subtypes in single-cell RNA sequencing (scRNA-seq) data remains challenging, as their subtle transcriptional differences a...
Next-generation MS platforms are transforming drug discovery by revealing complex biology earlier, faster, and at unprecedented depth. The post Mass Spectrometry’s Discovery Revolu...
by Zachary Hemminger, Haley De Ocampo, Fangming Xie, Zhiqian Zhai, Jingyi Jessica Li, Roy Wollman Motivation Most imaging-based spatial transcriptomics methods measure individual g...
Novel ways to discover undruggable protein targets are paving way for the next wave of proximity degraders. The post Are we ready for the next wave of proximity degraders? appear...
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