Scientists build mathematical model to track MS relapse patterns
A trio of scientists in Australia has developed a mathematical model that can be used to help understand disease activity patterns in people with multiple sclerosis (MS). The model...
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A trio of scientists in Australia has developed a mathematical model that can be used to help understand disease activity patterns in people with multiple sclerosis (MS). The model...
Daruwalla et al. Treatment escalation after clinically silent MRI lesions in relapsing-remitting multiple sclerosis. Brain. 2026 Jul 24:awag252. Clinically silent MRI lesions occur...
A test using data from 18 blood biomarkers to track disease activity in multiple sclerosis (MS) was able to distinguish true MS relapses from symptom worsening unrelated to active...
A trio of European scientists has linked subtle changes in the brain’s white matter — tissue rich in nerve cell projections — to early relapsing-remitting multiple sclerosis (RRMS)...
An experimental oral drug called remibrutinib outperformed the approved therapy Aubagio (teriflunomide) in reducing disease flare rates in two large, late-stage clinical trials inv...
After receiving positive regulatory feedback from the U.S. Food and Drug Administration (FDA), Oculis is planning to expand clinical testing of its experimental therapy privosegtor...
In analyzing brain MRIs on people with early relapsing-remitting multiple sclerosis (RRMS), two markers of ongoing inflammation may help identify those patients at a higher risk of...
People with relapsing-remitting multiple sclerosis (RRMS) who show even a single silent lesion on an MRI scan while taking a lower- or moderate-efficacy disease-modifying therapy (...
In MS we do not know of a definative target. But in neuromyelitis optic a demyelinating condition of the spinal cord and optic nerves is associated with antibodies against a water...
Vitamin D supplementation did not consistently reduce relapse rates in adults with multiple sclerosis (MS), although it may reduce the number of MS lesions seen on MRI scans, accor...
Rehabilitation strategies aimed at learning new skills may promote myelin repair in people with multiple sclerosis (MS), said scientists, who called for more research to test these...
Early treatment with high-efficacy disease-modifying therapies (DMTs) lowered the risk of relapse-associated disability progression in people with multiple sclerosis (MS), but had...
Maal AB, Arki MK, Nabavi SM, Rezaei-Tavirani M, Rismani E, Vosough M, Azizi G, Hossein-Khannazer N. Immune reconstitution and tolerance-inducing therapies as promising therapeutic...
Two years ago, the list of signs and symptoms required to diagnose a patient with the neurodegenerative autoimmune disease multiple sclerosis underwent a massive overhaul.Continue...
Ocrelizumab is licenced for relapsing and active primary progressive MS (Lesions and relapses) in the EU…It is active because we know it works by stopping B cells from entering the...
So I have been banging on about PIRA being a measure that incorporates the action of anti-inflammatory treatment and here the info says that high efficacy treatment inhibits relaps...
Controversy about the significance of lesions (inflammation) versus other (neurodegenerative) factors for the evolution and degree of disability in MS continues. Here, we have a gr...
People with relapsing-remitting multiple sclerosis (MS) may have less diverse gut bacteria than healthy people, with shifts in genes involved in how well certain bacteria break thr...
A little while ago, the new “McDonald” criteria were published. Here are our thoughts about the potential of moving the needle towards earlier detection, the risk of not getting it...
Hogenboom et al. Individual Variability of CD19+ B-Cell Repopulation in People With Multiple Sclerosis Treated With Extended Interval Dosing of Ocrelizumab. Eur J Neurol. 2026; 33:...
ProfK has ben magnifying the cladribine natural history and they have got back to where we left off in 2010, when they threw cladribine out with the bath water. They say that cladr...
Nerve damage is a consequence of poorly controlled MS and in one place it is easy to monitor nerve damage and this is in the eye. The eye is connected to your brain and nerve damag...
Elevated levels of a blood protein called GFAP are associated with an increased risk of disease progression in the absence of relapse activity in people with multiple sclerosis (MS...
A new experimental cell therapy that pairs a patient’s own red blood cells with myelin protein fragments safely calmed the immune system and helped dampen the inflammatory attack t...
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