Lesions and disability in MS are (partially) disconnected
Controversy about the significance of lesions (inflammation) versus other (neurodegenerative) factors for the evolution and degree of disability in MS continues. Here, we have a gr...
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Controversy about the significance of lesions (inflammation) versus other (neurodegenerative) factors for the evolution and degree of disability in MS continues. Here, we have a gr...
A specialized MRI technique detected signs of myelin and iron loss in nerve fibers beneath the brain’s outer layer in people with relapsing-remitting multiple sclerosis (RRMS), but...
Patterns in how different regions of the brain are structurally organized may help distinguish people with multiple sclerosis (MS) from those without the disease and provide inform...
A trio of European scientists has linked subtle changes in the brain’s white matter — tissue rich in nerve cell projections — to early relapsing-remitting multiple sclerosis (RRMS)...
In people newly diagnosed with relapsing-remitting multiple sclerosis (MS), a higher number of oligoclonal bands (OCBs) — bands of antibodies found in the fluid surrounding the bra...
In one of the largest neuropathological studies of multiple sclerosis ever undertaken, researchers examining autopsy brain tissue from 287 donors have uncovered compelling evidence...
Sound like time for MS base to get involved and sort this out as a matter Patel MA, Punnen TG, Shan KS, McCreary MC, Wright CM, Munoz SB, Hardeman P, Burgess KW, Greenberg BM, Hort...
A little while ago, the new “McDonald” criteria were published. Here are our thoughts about the potential of moving the needle towards earlier detection, the risk of not getting it...
Increased memory loss over longer periods, known as accelerated long-term forgetting (ALF), is greater in people with multiple sclerosis (MS) than in healthy adults, a study found....
Some paramagnetic rim lesions (PRLs) — MRI findings linked to chronic inflammation — disappeared in the brains of adults with multiple sclerosis (MS) after they underwent an autolo...
A fast-track diagnostic pathway that includes a specific MRI marker called the central vein sign (CVS) cut the average time to diagnose multiple sclerosis (MS) by about three month...
Vitamin D supplementation did not consistently reduce relapse rates in adults with multiple sclerosis (MS), although it may reduce the number of MS lesions seen on MRI scans, accor...
For years we have been searching and questioning new targets in multiple sclerosis. What is it?….Or is it what are they? Some people (Greeat & the Good) have told us myelin bas...
Sasha Clark was getting ready for work one morning in 2018 when she suddenly realised she couldn't see clearly. Just two months later, she was diagnosed with MS.
Studies show that nearly one in five MS patients are later told they don't actually have the condition - in some cases, after receiving treatment for MS for more than a decade.
Nerve damage is a consequence of poorly controlled MS and in one place it is easy to monitor nerve damage and this is in the eye. The eye is connected to your brain and nerve damag...
Parkinson's disease and Lewy body dementia are synucleinopathies, characterized by the spread of misfolded α-synuclein through the central nervous system. The presence of misfolded...
Living with a chronic illness such as multiple sclerosis (MS) — which is caused by the immune system erroneously attacking and damaging neurons in the brain and other parts of the...
Many years ago I dipped my toes into the stem cell World of control and it must have been an ice bath or acid as I lost my toes. At the time there was a lot of interest in mesenchy...
You know this already that HSCT (Stem cell transplants) are the most effective treatments to inhibit relapsing MS. In the study 6/24 had IgM oligoclonal bands and 50% became negati...
A large trans-disease meta-analysis of more than 6,900 brain scans finds that Alzheimer's disease and multiple sclerosis share a common grey matter atrophy pattern in the superior...
FRIDAY, Oct. 16, 2026 — Therapy targeting the immune system’s B cells might offer better odds against relapses in the early stages of multiple sclerosis (MS), a new study reports....
Amyotrophic lateral sclerosis (ALS) is characterized by the loss of motor neurons. Aggregation of TDP-43 is thought to be involved in producing cell death in the brain. Here resear...
Recently, TMS4All organised a meeting to discuss new approaches to takle delays in the diagnosis and treatment of MS. Ashvin Kuri from the Centre for Preventive Neurology at QMUL s...
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