What Is the Worst Pain Imaginable?
By Dr. Forest TennantIn the 1970’s, when I first started treating intractable pain, my first cases were the bone pain of metastatic cancer, usually melanoma, breast, or prostate ca...
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By Dr. Forest TennantIn the 1970’s, when I first started treating intractable pain, my first cases were the bone pain of metastatic cancer, usually melanoma, breast, or prostate ca...
By Pat Anson A new study has found what many chronic pain patients have already learned the hard way: It’s difficult to get a diagnosis.Researchers at The University of Texas at Ar...
As a pain management specialist, I see patients every week who feel like they have tried nearly everything. They come to me after months, or even years, of battling chronic or refr...
Pain is the body’s natural warning system. But what happens when that warning never switches off? Chronic pain defined as pain lasting more than 6 months is a medical condition in...
In “failing” this study delivered an important pain management insight for total hip arthroplasty surgeons…
By Neen MontyDoctors, policymakers, journalists, and pain experts endlessly warn about the risk of overdose from long term opioid therapy.But almost nobody talks about the risk of...
By Dr. Forest TennantOver the past 1-2 years, the fatty acid palmitoylethanolamide (PEA) was found to reduce pain and inflammation. PEA occurs naturally in our bodies and in some f...
By Madora Pennington“It’s called the ‘suicide disease’ because the pain is so bad people cannot live with it,” Susie Ruvalcaba tells me about Chronic Regional Pain Syndrome (CRPS),...
By Chris SeenanIn a 2026 study I conducted with colleagues on people with peripheral arterial disease, one participant described how leg pain had disrupted his golf for years. It f...
WEDNESDAY, April 29, 2026 — U.K. resident Fiona McNiven can tell you how chronic pain can wear a person down, as she spent more than three decades battling muscle and neuropathic p...
A publication in Nature in April 2026 reports that N-desethyl-fluornitrazene (DFNZ), a modified nitazene and µ-opioid receptor (MOR) superagonist, produced potent analgesia in rode...
Transarterial Embolization Using Imipenem/Cilastatin for Chronic Painful Achilles Tendinopathy Refractory to Conservative Management Neeraj Kumar et al Source RESEARCH H...
[GroundUp] Millions of South Africans suffer from chronic pain, and it's not being properly managed
Pain medicine has expanded rapidly in both scope and technical complexity over the past two decades. At the same time, uncertainty surrounding fellowship recruitment, workforce sta...
Imagine a 54-year-old construction worker named Mike living with debilitating chronic lower back pain after years on the job. His doctor recommends a targeted epidural steroid inje...
By Pat AnsonThe same academic institution that helped launch a nationwide crackdown on opioid medication has a new suggestion on how to treat chronic pain: hypnosis.Researchers at...
In a groundbreaking advance that could reshape the future of pain management, researchers led by Clarke, Mugglestone, and Lojkiewiez have demonstrated the capacity of multi-focal u...
“Women are now told if you take a couple of ibuprofen, you are fine with the pain. In reality, that is unlikely to be true,” says Professor Ben Mol, professor of Obstetrics and Gyn...
Knee osteoarthritis (OA) remains a leading cause of chronic pain and reduced mobility, affecting millions of adults worldwide, particularly those over age 50. As cartilage deterior...
By Brett Kelman and Amy Maxmen, KFF Health News Three weeks after Sophia Bassan’s mastectomy, she felt a stabbing pain beneath her right armpit. In the following months, painful sh...
Researchers have engineered a novel nitazene-based opioid, DFNZ, that provides potent pain relief without causing respiratory depression or addiction. The "superagonist" drug could...
By Dr. Lynn WebsterIn Greek mythology, the goddess Panacea carried a potion that could heal any disease. It’s a seductive image, and it’s how GLP-1 drugs can start to feel as repor...
By Pat AnsonPhysical therapy, cognitive behavioral therapy (CBT), and mindfulness are often recommended as non-pharmacological treatments for chronic lower back pain. The World Hea...
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