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Protein engineering improves AI-designed base editors, boosting precision and efficiency for more reliable nuclear and mitochondrial DNA editing.
Rather than requiring genetic modification of the viral glycoprotein, G-Link uses a modular protein adaptor to blind native VSV-G tropism and redirect delivery after vector product...
Avenue Biosciences´ machine learning-powered platform engineers and screens signal peptide variants to increase protein secretion from cells. Circio’s circVec technology has demons...
Scientists have created a platform that can rapidly assess bacterial traits and pinpoint genetic triggers that turn microbes into efficient factories for biotech applications inclu...
DNA regulatory elements, which control when, where, and to what extent specific genes are turned on or off, can be co-opted by scientists to create gene switches. The post Gene Sw...
A group of academic researchers genetically engineered Alteromonas macleodii, a widespread marine bacterium, to produce more siderophores, accelerating olivine weathering 2.6-fold...
Rothamsted Research is claiming a boost for its gene editing development programmes concerning the “evolution” of new cereal varieties. This follows the granting by UK regulators o...
Developed de novo using the company’s proprietary transcriptional analysis and sequence engineering platform, SynGenSys’ CHO.SET synthetic promoters combine advanced computational...
Manufacturing costs for therapies based on adeno-associated viruses (AAV) could fall thanks to careful work on plasmid redesign and cell-line selection by a company with long-term...
Scientists used artificial intelligence to design CRISPR nucleases with properties not found in nature, achieving activity that matches or exceeds natural enzymes despite the prote...
To produce stable cell lines for monoclonal antibody production, manufacturers typically use the piggyBac transposon system. For larger, multi-specific antibodies that have payload...
A new extracellular secretion system could help biopharmaceutical manufacturers bypass the problems that make traditional Escherichia coli-based recombinant endonuclease production...
A new mathematical model tracks how plasmids move through competing E. coli populations, revealing how antibiotics, genetic costs, and plasmid loss could shape biotechnology cultur...
Generating biomanufacturing-relevant data on protein production in a large-scale, AI-enabled database is still rare. When commercialized, it may substantially improve development t...
Using genetic engineering to drive at least some pest species to extinction is ethical.
The collaboration brings together Synastra’s expertise in genomic engineering, AAV vector design, rare-disease gene therapy, and translational development with NewBiologix’s propri...
Solar energy generates electricity to produce hydrogen, which combines with carbon dioxide to make methanol. Specialized enzymes then convert methanol into specific amino acids, de...
Saudi Arabia is pairing gene editing breakthroughs with new biomanufacturing capacity, from CRISPR oncology therapies to CDMOs like Lifera, as it builds a full biotech pipeline. Th...
Traditional gene editing rewrites DNA. But a new approach, called epigenome editing, aims to treat the molecular scars we collect throughout our lives.
DNA Script says the company is contributing its EDS technology and acting as a technical solution integrator for the project, while adapting its solution to incorporate GE HealthCa...
A new study reports a strategy for delivering gene-editing technology directly to human haematopoietic stem cells inside the body, using targeted lipid nanoparticles rather than vi...
Technologies like CRISPR are giving us new ways to create the dogs of our dreams — and a reason to reckon with our past mistakes.
In this GEN webinar, speakers from Flock Bio and Ribbon Bio will explore how bench-based, cell-free DNA production can complement expertise in custom DNA design and manufacturing....
ICAR is expected to sign a MoU this month with US-based Corteva, which holds the license for the CRISPR-Cas9 gene-editing technology
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