Social Media Ideas for Gain Of Function Research

Hey, Great News! Scientists Used AI to Create Viruses

What about attempts to test their virulence in humans? The approach in the Stanford lab sure sounds like a new form of gain-of-function research to me. Source

RAS Rewires Ribosomes, Reshaping How Cells Read the Genetic Code

Cancer cells may be able to reprogram more than gene activity and signaling networks. A study led by researchers at Fudan University and Zhongshan Hospital in Shanghai reports that...

Flu Virus Interaction with Host Cell Machinery Mapped Inside Infected Cells

Researchers developed a customized experimental workflow combining cross-linking mass spectrometry with AlphaFold-based structural modeling and functional assays to directly map pr...

Identifying severe COVID-19 risk variants modulating enhancer reporter activity in lung cells

by Giovanna Weykopf, Wendy A. Bickmore, Simon C. Biddie, Elias T. Friman Common genetic variants contribute to risk for complex human diseases. However, despite thousands of assoc...

Report: Bill Gates Given Top Security Clearance During Dangerous 'Gain of Function' Virus Research

Microsoft co-founder and private citizen Bill Gates received top security clearance from the Department of Energy (DOE), giving him access to deep government secrets for seven year...

Study Suggests Every $1 Spent on U.S. WGS Foodborne Pathogen Surveillance Generates $31 ROI

The researchers analyzed cost and sequencing-volume data from 23 FDA and FDA partner GenomeTrakr laboratories. Findings suggested that WGS-based genomic surveillance is a cost-effe...

Immune Evasion Uncovered by Virome-Wide Ubiquitin Ligase Discovery

Viruses hijack cells’ garbage-disposal systems to evade immune attack. The study proposes to speed basic discoveries in virology, and inform the development of new vaccines and tre...

How to Stop a Lab Leak From Starting the Next Pandemic

More than six years after the emergence of Covid-19, no one is keeping track of the risky virus experiments that are capable of starting a pandemic.

Engineered helper plasmid boosts AAV production by tuning E4orf6 and L4-22/33K expression

A redesigned helper plasmid has increased the production of adeno-associated virus (AAV) vectors by controlling the relative expression of two adenoviral regulatory factors, accord...

Scientists are using AI to design new viruses. Should they be?

Research is outpacing regulation to govern artificial-intelligence-designed biology

AI used to create never-before-seen synthetic viruses that can multiply faster than natural ones

Urgent biosafety concerns raised over future of technology

AI Designed a Virus Genome No One Had Seen Before. Researchers Made It Work

Scientists at Stanford University and the Arc Institute have crossed a line that, until this week, existed only as a possibility. They used artificial intelligence to design comple...

Rand Paul: I Think Intel. Agencies Are Still Doing Gain of Function, 'They Won't Give Me Proper Oversight'

On Thursday’s broadcast of CNBC’s “Squawk Box,” Sen. Rand Paul (R-KY) stated that he believes that American intelligence agencies are still doing gain of function research on monke...

Gene Therapy Partners Aim to Enhance Protein Expression

Avenue Biosciences´ machine learning-powered platform engineers and screens signal peptide variants to increase protein secretion from cells. Circio’s circVec technology has demons...

Ministry to enhance safety at laboratories studying pathogens

EDITORIAL: Fauci-Paul clash obscures the larger question

Federal funding of potentially dangerous research.

AI creates first synthetic viruses

Genomic language model has huge potential to redesign organisms such as bacteria

Inhaled Suppressor tRNA Restores Gene Function in Cystic Fibrosis Models

A preclinical study showed how chemically enhanced suppressor tRNAs combined with a lung-targeted delivery system can restore production of a critical protein in models of cystic f...

Leveraging synthetic and genetic data to improve epidemic forecasting

by Dave Osthus, Alexander C. Murph, Emma E. Goldberg, Lauren J. Beesley, William M. Fischer, Nidhi Parikh, Lauren A. Castro Forecasting infectious disease outbreaks is hard. Forec...

Novel electromagnetically tunable gene switch enables precise control of gene expression

Single-cell RNA sequencing identified an electromagnetic field-responsive gene, enabling researchers to develop a reversible switch for precise, non-invasive control of gene expres...

Tick-Borne Nairoviruses Use OTU Proteases to Evade Human Antiviral Signals

Beyond familiar tick‑borne diseases, nairoviruses are quietly rising. New biochemical and structural work shows how their OTU proteases strip immune‑signaling tags, offering a foun...

‘Delete From The Deleted File’: Fauci Tried To Destroy Gain-Of-Function Research Email, New Docs Reveal

by Emily Kopp at CDN - Eight years before COVID emerged, a journalist issued a prophetic warning that risky viral research could usher in “doomsday” and damage the reputation of t...

Researchers get two genetic codes to work at the same time

Messing with the genetic code might have gotten a bit easier to do.

Our Most Dangerous Labs Have a Problem No One Wants to Fix

A worker at a US government lab got bitten by a monkey carrying a deadly virus, and it turned out nobody knew what to do about it. Around the same time, someone from the same lab t...