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  • Small Brønsted bases activate GTP hydrolysis in KRAS-Q61 mutants

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bioengineer.org /4 weeks ago

Small Brønsted bases activate GTP hydrolysis in KRAS-Q61 mutants

KRAS has long been one of cancer biology’s most stubborn molecular targets. The protein acts as a switch that helps cells interpret growth signals, cycling between an active state...

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