Latest updates for Functional Genomics

Fresh curated links around Functional genomics are collected here so marketers can spot useful updates and turn timely ideas into posts faster.

Recent items include:

  • Transcriptomic Approaches to Guiding the Discovery of Geroprotective Compounds
  • Multiomics in 2026 and Beyond
  • Functional genomics maps broad, convergent asciminib resistance mechanisms in BCR::ABL1

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fightaging.org /1 week ago

Transcriptomic Approaches to Guiding the Discovery of Geroprotective Compounds

A great deal of drug discovery starts by screening compounds from the vast libraries of molecules that exist. The libraries are too large to screen everything (and even then the sc...

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genengnews.com /1 week ago

Multiomics in 2026 and Beyond

Multiomics analysis combines data from two or more omics layers—such as genomics, transcriptomics, proteomics, and epigenomics. However, published criticisms of multiomics approach...

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bioengineer.org /1 month ago

Functional genomics maps broad, convergent asciminib resistance mechanisms in BCR::ABL1

A sweeping genetic map of drug resistance in chronic myeloid leukemia has revealed that cancer cells can evade asciminib through mutations scattered across much more of the BCR::AB...

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nanowerk.com /1 month ago

A Google-like search engine for single-cell RNA

Scientists have built a search engine that can scan data from millions of single cells from thousands of experiments worldwide in seconds. The tool makes it possible to answer prev...

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genengnews.com /2 weeks ago

The Epitranscriptome Heads Toward Clinical Necessity

Short-read RNA sequencing reporting the modifications that alter protein output is starting to make epitranscriptomics indispensable for patient selection in precision medicines. T...

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rna-seqblog.com /1 month ago

New method allows scientists to follow gene activity over time in the same cells

Live-cell RNA sequencing uses engineered virus-like particles to repeatedly sample transcriptomes without destroying cells, enabling researchers to track gene expression changes ov...

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rna-seqblog.com /1 month ago

RNA sequencing reveals functional chimeric mRNAs in mammalian immunity

Direct RNA sequencing revealed thousands of chimeric mRNAs in mammalian cells, uncovering previously unknown proteins with roles in immunity, inflammation, and potential drug disco...

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webwire.com /1 month ago

New method allows scientists to follow gene activity over time in the same cells

The following press release was issued by the Broad Institute of MIT and Harvard. - - In recent years, scientists have built methods to measure a cell's transcriptome, or all t...

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rna-seqblog.com /3 weeks ago

The Human RNome Project Consortium seeks to publish first-ever complete sequence of the body’s RNA

RNA sequencing efforts from the Human RNome Project aim to build a comprehensive reference of human RNA sequences, isoforms, processing states and chemical modifications...

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genengnews.com /2 weeks ago

DNA Typewriter, PEtracer Map Mouse Development Through Organogenesis

Two DNA-recording systems traced cellular family trees across mouse embryogenesis, offering new insight into how organs form and when developing cells commit to specific fates. The...

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rna-seqblog.com /3 days ago

Exercise is good for us—but why?

RNA sequencing and multi-omics profiling reveal how exercise alters gene expression, metabolism and epigenetic regulation across 22 tissues, identifying molecular signatures of exe...

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rna-seqblog.com /1 month ago

A functionally integrated cross-tissue alternative splicing program during short-term calorie restriction

RNA sequencing reveals that calorie restriction drives dose-responsive alternative splicing across multiple tissues, affecting mitochondrial, translational, and RNA quality-control...

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genengnews.com /1 week ago

Thirty Million Compartments: Testing Single-Molecule PCR’s Potential

Countable Labs has named Fred Hutchinson its first certified service provider, currently serving researchers across the Seattle region. And the company is continuing to build its l...

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rna-seqblog.com /2 weeks ago

GP-DHT uses single-cell RNA sequencing to map gene regulatory networks

Single-cell RNA sequencing combined with GP-DHT helps predict transcription factor and target gene relationships, providing a...

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phys.org /3 weeks ago

Catalog of mitochondria across life's family tree unearths unusual functions

A research consortium has generated the broadest look yet at the proteins that make up mitochondria, capturing the organelle's diversity across multiple branches on the tree of com...

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genengnews.com /1 month ago

RNAV8 Bio Joins ARPA-H Team to Pioneer Programmable RNA Medicines

The PROPEL program aims to control gene expression through RNA structure, building logic-gated RNA therapies that switch on only where and when intended, without altering the genom...

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rna-seqblog.com /1 week ago

Bulk RNA-seq Analysis: A Complete Beginner’s Guide

Bulk RNA sequencing helps researchers identify gene expression patterns associated with differences in drug response, supporting biomarker discovery and personalized medicine while...

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rna-seqblog.com /2 weeks ago

Tracing 700 million years of cell evolution

RNA sequencing combined with AI helps Unify compare cell types across distant species by identifying shared biological functions even when individual genes no longer directly...

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rna-seqblog.com /2 weeks ago

Novel biosensor uses DNA ‘barcodes’ to uncover disease signals in cells

RNA sequencing can read Detectron-generated DNA barcodes, enabling scalable detection of specific RNA signals associated with infection, gene activity and other cellular processes....

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rna-seqblog.com /1 month ago

A real-data approach to evaluating RNA transcript analysis methods

RNA sequencing data provide a real-world framework for comparing differential transcript usage methods across bulk, single-cell, spatial, long-read, and short-read transcriptomics....

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genengnews.com /1 month ago

Spatial Transcriptomics Tools May Link Tumor Organization to Treatment Response

A new spatial transcriptomics framework compares tumor “floor plans." In a study of 262 solid tumors, the team identified recurring spatial groups that may connect spatial structur...

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bioengineer.org /1 month ago

Scientists characterize genetic variants across the human intrinsically disordered proteome

Variant effect prediction has entered a new phase, but one of biology’s largest blind spots remains stubbornly difficult to resolve. Computational tools have become increasingly ef...

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journals.plos.org /2 weeks ago

HiFIseek: Gene-specific enrichment of high-impact mutations in associated genomic regions

by Rafael Riudavets Puig, Denise G. O’Mahony, Ina Skaara Brorson, Ksenia Sokolova, Vessela N. Kristensen, Anthony Mathelier Transcription is regulated through the sequence-specifi...

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rna-seqblog.com /1 month ago

POND-seq enables non-destructive RNA sequencing in living cells

POND-seq enables non-destructive RNA sequencing of living cells, allowing repeated measurement of transcriptomes and RNA-binding protein interactions as cells respond to changing c...

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Sources covering Functional Genomics

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bioengineer.org

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feeds.feedburner.com

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journals.plos.org

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phys.org

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fightaging.org

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