A Newer Kind of Gene Editing Promises to Edit ‘Nurture’ Over ‘Nature’
Traditional gene editing rewrites DNA. But a new approach, called epigenome editing, aims to treat the molecular scars we collect throughout our lives.
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Traditional gene editing rewrites DNA. But a new approach, called epigenome editing, aims to treat the molecular scars we collect throughout our lives.
Cancer has long been understood as a disease of the genome, driven by mutations that rewire the instructions encoded in DNA. Over the past three decades, however, a parallel truth...
The presently available data and understanding of aging might be thought of as a jigsaw with more missing pieces than there are pieces in hand. There is a great deal of latitude to...
by Rochelle E. Yap, Felicia Ebot-Ojong, Abigail J. Ameri-Solanky, Zachary A. Lewis In animals, plants, and some fungi, Polycomb Repressive Complex 2 (PRC2) catalyzes trimethylatio...
by Syeda Kubra, Michelle Sun, William Dion, Yu Bian, Ahmet Catak, Hannah Luong, Haokun Wang, Yinghong Pan, Jia-Jun Liu, Aishwarya Ponna, Lijun Liu, Ian Sipula, Jian-Hua Luo, Michae...
Two DNA-recording systems traced cellular family trees across mouse embryogenesis, offering new insight into how organs form and when developing cells commit to specific fates. The...
Earlier in this series I killed a brain and the memory lived through it. Then I dropped that memory into a fresh brain, and the fresh brain woke up believing a life it never lived...
In the earliest hours of a sea lamprey embryo’s life, something remarkable happens. As its cells divide, vast stretches of genetic material—entire chromosomes—are...
You are the science news desk of a major English-language science magazine. Complete the task immediately. Never ask the reader what to do, never offer editing options, and never r...
A new computational framework that identifies minimal temporary gene-control interventions to steer cells toward desired states while preserving cellular plasticity.
SKIN THE ARCHITECT is an interactive installation by LAIDA - the Latvian Architecture and Design Union - created in response to the theme of this year's Tallinn Architecture Bienna...
New findings could change how scientists think about DNA organization, transcription, and genome function.
by Luisa Quesada Camacho, Mohammad Fallahi-Sichani Epigenetic dysregulation is a common feature of cancer. It creates vulnerabilities arising from an increased reliance on chromat...
by Phillip L. Davidson, Isabel G. Manley, Armin P. Moczek Condition-responsive growth is a common feature of multicellular development, during which organisms integrate genetic an...
Cambridge, MA – MIT Media Lab – EmTech Future. Nature has spent roughly 3.8 billion years conducting the most sprawling, creative research and development campaign in history. Evol...
Aging clocks have yet to fulfill their promise, which is to produce a robust measure of biological aging that can be used to rapidly assess the results of potential therapies to sl...
ARCADIA integrates single-cell RNA sequencing with spatial proteomics to reveal how tissue neighborhoods influence B-cell maturation, T-cell activation, and other transcriptional p...
The daily rhythms that govern life on Earth—from the sleep-wake cycles of humans to the emergence of insects from their pupal cases—are orchestrated by an internal molecular timeke...
Written in genetic code.ScienceAlert stories are written, fact-checked, and edited by humans, never generated by AI. Don't miss a story, subscribe here.
by Lu Chai, Jie Gao, Tinghe Guo, Teer Ba, Zihan Li, Junjie Liu, Yong Wang, Lirong Zhang CTCF is a key architectural protein with diverse roles in genome organization and gene regu...
Short-read RNA sequencing reporting the modifications that alter protein output is starting to make epitranscriptomics indispensable for patient selection in precision medicines. T...
Large dogs tend to be shorter lived than their smaller counterparts, and a new study found that male and larger dogs undergo accelerated molecular aging, with pronounced DNA methyl...
"Take your dream suppressants." The opening line in Wanuri Kahiū's Pumzi, directed at our protagonist Asha, enforces the order of severing ties with hopeful futures and ancestral...
A comparative study in two beetle species links evolving regulatory DNA and condition-specific chromatin changes to horn diversification, with functional evidence for two BMP-pathw...
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