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Endothelial cells derived from women with PCOS harbor a latent mitochondrial defect that hyperglycemia unmasks, and blocking the enzyme myeloperoxidase restores their function in a...
by Yu-yuan Zhang, Yi-Teng Wang, Yan Qiu, Yong-Jiang Li, Dong Chen, Kai-Rong Qin Endothelial dysfunction is a critical initiating event in atherosclerosis. The regulatory role of t...
Retinal vascular findings can offer important clues about a patient’s systemic health. Kerry Gelb, O.D., explains how endothelial function testing can provide additional insight in...
Atherosclerosis is universal; everyone develops fatty atherosclerotic plaques in their arteries at some point, and to some degree. Plaques narrow blood vessels to impede blood flow...
Humanity is poorly supported by its vasculature. Vascular aging is the primary cause of human mortality, giving rise to atherosclerosis, the formation of fatty plaques that narrow...
Impaired microvascular flow motion in subclinical diabetic feet with sudomotor dysfunction. Sun PC, Chen CS, Kuo CD, Lin HD, Chan RC, Kao MJ, Wei SH. Microvasc Res. 2012 Mar;83(2...
A newly identified PI16-expressing reactive endothelial cell state with strong circadian gene activity supports neuronal survival and reduces brain injury in mouse models of ischem...
Cardiovascular Autonomic Dysfunction Predicts Diabetic Foot Ulcers in Patients With Type 2 Diabetes Without Diabetic Polyneuropathy. Yun JS, Cha SA, Lim TS, Lee EY, Song KH, Ahn Y...
Atherosclerosis is the largest cause of human mortality, producing stroke and heart attack when fatty plaques obstructing arteries rupture. There is accordingly a great deal of res...
A clinical study finds that mitochondrial function in leg muscle adapts after revascularisation only in earlier stages of peripheral arterial disease, while severe chronic limb-thr...
Atherosclerosis, the growth of fatty plaques in blood vessel walls, is the largest cause of human mortality. Unstable plaques rupture to block blood vessels to cause a heart attack...
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