Social Media Ideas for Drug Discovery

Drug discovery Is changing. Drug development must change too.

In this New Scientist CoLab podcast, experts from global life sciences leader Cytiva explain the hidden, high-stakes science of purification that is required to close the gap betwe...

Peptris is using AI to find drug candidates to shorten the time it takes for laboratory validation

The Bengaluru-based company builds models that generate molecules and predict how they will behave, and has licensed its lead candidate to a US developer.

<![CDATA[The Path from Discovery to Global Commercialization]]>

Blue Light Breakthrough Could Speed Up Drug Discovery

Researchers have developed a visible-light-driven method that could help chemists build more complex drug-like molecules in fewer steps. A blue light commonly used in aquariums and...

Genome Mining Points to Less Toxic, More Potent Polyene Antifungals in Mice

The researchers identified Nys34 as a leading candidate after it demonstrated three-to-eightfold lower toxicity than amphotericin B in multiple human cell lines and reduced fungal...

Receptor.AI and Sethera Plan to Create Closed-Loop Discovery and Optimization Workflow for Difficult Therapeutic Targets

The collaboration is specifically focused on applying Receptor.AI's computational platform to Sethera's proprietary polymacrocyclic peptide chemistry, encoded screening data, and r...

<![CDATA[The Full Path of Drug Development, and Why So Few Drugs Make It: Q&A with Dr. Ying Huang]]>

Inaugural AACR D3 Opens With Insights From Leaders Across Drug Discovery and Development

During the opening session of the AACR Conference on Drug Discovery and Development, the conference cochairs—Patricia M. LoRusso, DO, PhD (hc), FAACR; Keith T. Flaherty MD, FAACR;...

With $263M, LifeMine unearths a new drug for organ transplants

Led by serial biotech entrepreneur Greg Verdine, the startup mined fungi genomes to find a safer alternative to the drugs widely used to prevent the body from rejecting transplante...

A unified framework for potency-oriented AMP discovery via multi-modal learning and guided sequence synthesis

by Wenyu Zhang, Yizheng Wang, Yixiao Zhai, Pinglu Zhang, Yijie Ding, Quan Zou The rapid emergence of drug-resistant pathogens poses a critical threat to global health. With tradit...

<![CDATA[Finding the Universal Truth in a Drug's Story]]>

Elix and University of Vienna Aim to Advance Drug Discovery Using AI

Elix and the University of Vienna will partner to bridge the gap between advanced structural biology and artificial intelligence. By integrating AI’s predictive power with experime...

AI is not the beginning of drug discovery — it is the accelerator

Artificial intelligence is often framed as the technology that suddenly changed drug discovery. But that narrative misses an important truth: computational, or in silico, drug disc...

Discovery Paves Way for Drug Therapies for Hypopigmentation Conditions

Ampyrone—an NSAID-related compound—has emerged as a promising way to enhance melanin production in human skin, according to a preclinical study led by Weill Cornell Medicine and Na...

Novel Molecular Glue Discovery Platform Unlocks Undruggable Cancer Targets

A scalable platform to discover molecular glue degraders has been developed, identifying the first metabolically activated glue. The approach expands protein degradation targets, e...

<![CDATA[Roundup: Amplitude Therapeutics, Chai Discovery Enter Collaborations with Eli Lilly, Bristol Myers Squibb]]&...

DeepCyte Launches Single-Cell Metabolomic Reference Atlas of Drug Toxicity Mechanisms

Rather than generating new wet-lab data for every compound, DeepCyte trains a foundation model that is capable of predicting toxicity mechanisms for compounds that it has never mea...

How Drug Abuse by Bicyclists Led to a Medicine for Psychosis

There are many pathways to the discovery of new drugs, from intuitive trials based on unrelated observations to systematic molecule modification based on biochemical theories.

Centrix and University of Sussex Collaborate to Drive Data-Driven Pharma Development

The KTP provides access to academic expertise while embedding that capability within Centrix’s business. This project represents an opportunity to apply advanced data science techn...

Rznomics Joins Lilly Gateway Labs to Quicken RNA Therapeutic Candidate Discovery and Development

Through its entry into Lilly Gateway Labs, Rznomics officials say they plan to accelerate candidate discovery and development across its target gene database bank comprising over 2...

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

by Miriam C. Aziz, Jennie Wilson, Clement Y. Chow PIGA-CDG is a congenital disorder of glycosylation caused by pathogenic partial loss-of-function variants in the PIGA gene. PIGA...

Integrating chemical structures as treatments improves representations of microscopy images for morphological profiling

by Yemin Yu, Emre Hayir, Neil Tenenholtz, Lester Mackey, Ying Wei, David Alvarez-Melis, Ava P. Amini, Alex X. Lu Recent advances in self-supervised deep learning have improved our...

Software firm designed medicines, overcoming skull’s limitations

Anthropic has just published the results of a protein design campaign. Fifteen targets, a written brief and an instruction to design small proteins that latch onto them. The model...

AI Advances Revolutionize Oncology Drug Discovery from Targets to Therapies

Artificial Intelligence Revolutionizes Cancer Drug Discovery, Paving the Way for Next-Generation Therapies The arduous journey of developing effective cancer drugs, marked by high...