Migrating Nerve Cells Experience Routine, Repairable DNA Damage
The physical migration of newborn neurons through dense brain tissue causes routine, widespread double-strand DNA breaks.
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The physical migration of newborn neurons through dense brain tissue causes routine, widespread double-strand DNA breaks.
In a groundbreaking study published in Nature, researchers have illuminated the subtle yet profound effects of confined cellular migration on the genomic integrity of developing ne...
Researchers have captured the first atomic-level views of human SMUG1, a key enzyme involved in repairing damaged DNA. Every cell in your body is constantly battling damage to its...
Damage to DNA in cancer cells can lead to pieces breaking off chromosomes and floating away, like icebergs cracking off a glacier. Just as icebergs are a threat to ships and their...
Scientists have discovered that a gene normally considered a DNA-protecting "good guy" can become dangerous when cells make too much of it. The gene, EXO1, acts like molecular scis...
by Safia Mahabub Sauty, Jacqueline Shine, Hamed Bostan, Jian-Liang Li, Piotr A. Mieczkowski, Richard F. Loeser, Brian O. Diekman, Dmitry A. Gordenin DNA damage lesions can result...
by Sophia R. Martinez-Whitman, Chloe M. Santana, Alyssa P. Campbell, Denholm T. Feldman, Isaac E.Z. Jabaley, Luke G. O’Neal, McKayla E. Marrin, Elizabeth S. Thrall One challenge t...
by Laura Chastant, Karine Normandin, Firas El-Mortada, Marc J. Servant, Vincent Archambault Cellular damage or stress can lead to disorganization, mislocalization or damage to sel...
Researchers here report on an interesting in vitro exercise in the comparative biology of aging. They took fibroblast cells from ten difference mammalian species with widely diverg...
A new study suggests melatonin supplements may help night shift workers boost their body's DNA repair processes, potentially offsetting some of the damage linked to working overnig...
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