Search results for Clinical Trials

FDA Announces Real-Time Clinical Trial Pilot Program and Proof-of-Concept Studies with AstraZeneca and Amgen

What You Should Know The FDA has launched two proof-of-concept (PoC) real-time clinical trials (RTCT) that report endpoints and data signals to the agency as they occur. AstraZenec...

Pragmatic Trials

Publisher: The New England Journal of Medicine Published: 2016 This analysis explains the methods used for trials that inform a clinical or policy decision by providing evidence...

Real-time trials may ‘fundamentally transform’ research

An FDA initiative to implement real-world clinical trials could dramatically accelerate the pace at which new treatments become available to patients, according to physicians from...

FDA announces real-time clinical trials, request for information

The Food and Drug Administration April 28 announced its plan to advance the implementation of real-time clinical trials, which invite participants to supply reports and data to the...

How To Find A Clinical Trial That Actually Prioritizes Your Safety

If you’ve ever wondered how new medications, treatments or medical devices actually make it to your doctor’s office, the answer almost always starts with clinical trials.

Most patients with pancreatic cancer not offered clinical trials

Most patients with pancreatic cancer report they were never offered the opportunity to participate in clinical trials.A survey of more than 1,000 patients showed greater than 70% n...

FDA Moves to Real-Time Clinical Trial Patient Monitoring, Faster Drug Review

WEDNESDAY, April 29, 2026 — The U.S. Food and Drug Administration (FDA) is moving to speed drug development and review by launching real-time clinical trials. The move could soon...

Q&A: New JAMA resource shows ‘labor of love’ behind clinical trials

JAMA Network announced a new resource called JAMA+ Trials that is “designed to elevate the visibility, accessibility and understanding of trusted clinical trial research across med...

FDA tests out ‘real-time’ clinical trials; AbbVie closes in on a KRAS biotech

Through two pioneering studies, Amgen and AstraZeneca will share study data with FDA scientists as it’s accrued. Elsewhere, Lilly inked a gene editing deal and Pfizer reported succ...

FDA Moves Toward Real-Time Clinical Trial Modernization

On April 28, 2026, the U.S. Food and Drug Administration (“FDA”) announced additional steps in its ongoing initiative to advance real-time clinical trial approaches, including proo...

FDA Makes Moves to Modernize Drug Development, Clinical Trial Paradigm

On April 28, 2026, the Food and Drug Administration (FDA) unveiled two major announcements as part of its initiative to “advance the implementation of real-time clinical trials.” I...

Academic Clinical Trials for Rapamycin to Answer Questions on Dosing for Anti-Aging Use

Rapamycin is increasingly prescribed off-label by anti-aging physicians based on animal studies and very limited human data (even including the relatively recent crowdfunded PEARL...

Small pools, big ideas: How the rare disease community is reimagining clinical trials

The traditional gold standard of clinical trials with a randomized, placebo-controlled design involving hundreds of patients has inherently been unfeasible for the rare disease com...

Clinical Trials Were Used as Marketing Ploys for Gabapentin and Other Drugs

By Sukhun KangSome clinical trials aren’t designed to answer scientific questions. They’re designed to market drugs. In our recently published research, my team and I analyzed over...

New Trial Prevents Cognitive Decline in Older Cancer Patients

In a groundbreaking multicentric randomized controlled trial, researchers have embarked on a novel exploration of cognitive preservation among older Indian patients with cancer und...

FDA urges clinical trial sponsors to report the results of their studies

An FDA review of records found that results have not been reported for 30% of registered clinical studies. To remedy this shortfall, the U.S. regulator has sent reminders to 2,200...

Trial of Novel Bispecific Therapy for Resistant Ovarian Cancer

In a groundbreaking stride against one of oncology’s most formidable challenges, researchers have unveiled promising clinical trial results exploring novel immunotherapeutic strate...

Innovative Approach Enhances Health Research in Rural Communities

Randomised controlled trials (RCTs) have long been hailed as the pinnacle of clinical research, setting the gold standard for evaluating the efficacy of medical interventions. Howe...

What Are the Top Drugs in Phase 3 Trials in the U.S.?

What Are the Top Drugs in Phase 3 Trials in the U.S.? Anonymous (not verified) Sat, 05/02/2026 - 14:19 pharmagather item url What Are the Top Drugs in Phas...

Let us go back to the golden age of simple clinical trials & get rid of big, motivated RCTs.

Very soon, blogs and independent writing will be the only source of unadulterated truths. One such article is shared here written by Adam Kroetsch , formerly in the FDA A review an...

<![CDATA[ What Design Choices Made the MajesTEC-3 Trial Clinically Compelling?]]>

Rethinking dermatology trial design for late-stage success

A smarter approach to dermatology trials—built for durability and real-world impact.

<![CDATA[The Difference Between Real-Time Clinical Data Review and Real-Time Clinical Trial Oversight]]>

<![CDATA[Does FDA's Shift From Two Pivotal Trials to One Represent a Genuine Evolution?]]>