Search results for Clinical Trial

FDA Announces Real-Time Clinical Trial Pilot Program and Proof-of-Concept Studies with AstraZeneca and Amgen

What You Should Know The FDA has launched two proof-of-concept (PoC) real-time clinical trials (RTCT) that report endpoints and data signals to the agency as they occur. AstraZenec...

How To Find A Clinical Trial That Actually Prioritizes Your Safety

If you’ve ever wondered how new medications, treatments or medical devices actually make it to your doctor’s office, the answer almost always starts with clinical trials.

Trial of Novel Bispecific Therapy for Resistant Ovarian Cancer

In a groundbreaking stride against one of oncology’s most formidable challenges, researchers have unveiled promising clinical trial results exploring novel immunotherapeutic strate...

New Trial Prevents Cognitive Decline in Older Cancer Patients

In a groundbreaking multicentric randomized controlled trial, researchers have embarked on a novel exploration of cognitive preservation among older Indian patients with cancer und...

FDA Moves to Real-Time Clinical Trial Patient Monitoring, Faster Drug Review

WEDNESDAY, April 29, 2026 — The U.S. Food and Drug Administration (FDA) is moving to speed drug development and review by launching real-time clinical trials. The move could soon...

A Randomized Trial of Colonoscopy versus Fecal Immunochemical Testing versus Usual Care in the Detection of Colorectal C...

Most patients with pancreatic cancer not offered clinical trials

Most patients with pancreatic cancer report they were never offered the opportunity to participate in clinical trials.A survey of more than 1,000 patients showed greater than 70% n...

Real-time trials may ‘fundamentally transform’ research

An FDA initiative to implement real-world clinical trials could dramatically accelerate the pace at which new treatments become available to patients, according to physicians from...

Pragmatic Trials

Publisher: The New England Journal of Medicine Published: 2016 This analysis explains the methods used for trials that inform a clinical or policy decision by providing evidence...

Health Spotlight | Clinical trial shows near-complete response in colorectal cancer patient

A young father with advanced colorectal cancer is participating in a groundbreaking clinical trial using immunotherapy, which has resulted in a near-complete response and could pot...

FDA tests out ‘real-time’ clinical trials; AbbVie closes in on a KRAS biotech

Through two pioneering studies, Amgen and AstraZeneca will share study data with FDA scientists as it’s accrued. Elsewhere, Lilly inked a gene editing deal and Pfizer reported succ...

FDA announces real-time clinical trials, request for information

The Food and Drug Administration April 28 announced its plan to advance the implementation of real-time clinical trials, which invite participants to supply reports and data to the...

Major milestone reached in Oxford University clinical trial

Oxford University Hospitals (OUH) has recruited its 100th patient to the EASi-KIDNEY study, which is evaluating a potential new treatment for chronic kidney disease (CKD).

<![CDATA[The Difference Between Real-Time Clinical Data Review and Real-Time Clinical Trial Oversight]]>

Dosing begins in trial testing treatment for MS, obesity

The first participant has been dosed in a Phase 1 clinical trial testing TNV262, an experimental therapy that Tenvie Therapeutics is developing as a potential treatment for multipl...

<![CDATA[Pharmaceutical Executive Daily: Zentalis Doses First Patient with Azenosertib in Phase III Trial]]>

First Human Trial of OSCA Therapy for Knee OA

In a groundbreaking advancement poised to transform the management of degenerative joint diseases, researchers have unveiled the first-in-human, multicenter phase I clinical trial...

<![CDATA[ What Design Choices Made the MajesTEC-3 Trial Clinically Compelling?]]>

in this issue

Applying data from clinical trials is intrinsically problematic because the benefits of an intervention are presented as group averages and do not describe how an individual patien...

<![CDATA[First Patient Dosed with Azenosertib in Aspenova Phase III Trial for Treatment of Ovarian Cancer]]>

Small pools, big ideas: How the rare disease community is reimagining clinical trials

The traditional gold standard of clinical trials with a randomized, placebo-controlled design involving hundreds of patients has inherently been unfeasible for the rare disease com...

Let us go back to the golden age of simple clinical trials & get rid of big, motivated RCTs.

Very soon, blogs and independent writing will be the only source of unadulterated truths. One such article is shared here written by Adam Kroetsch , formerly in the FDA A review an...

FDA Makes Moves to Modernize Drug Development, Clinical Trial Paradigm

On April 28, 2026, the Food and Drug Administration (FDA) unveiled two major announcements as part of its initiative to “advance the implementation of real-time clinical trials.” I...

Innovative Approach Enhances Health Research in Rural Communities

Randomised controlled trials (RCTs) have long been hailed as the pinnacle of clinical research, setting the gold standard for evaluating the efficacy of medical interventions. Howe...