Search results for Clinical Trials

FDA Announces Real-Time Clinical Trial Pilot Program and Proof-of-Concept Studies with AstraZeneca and Amgen

What You Should Know The FDA has launched two proof-of-concept (PoC) real-time clinical trials (RTCT) that report endpoints and data signals to the agency as they occur. AstraZenec...

Pragmatic Trials

Publisher: The New England Journal of Medicine Published: 2016 This analysis explains the methods used for trials that inform a clinical or policy decision by providing evidence...

How To Find A Clinical Trial That Actually Prioritizes Your Safety

If you’ve ever wondered how new medications, treatments or medical devices actually make it to your doctor’s office, the answer almost always starts with clinical trials.

FDA announces real-time clinical trials, request for information

The Food and Drug Administration April 28 announced its plan to advance the implementation of real-time clinical trials, which invite participants to supply reports and data to the...

Most patients with pancreatic cancer not offered clinical trials

Most patients with pancreatic cancer report they were never offered the opportunity to participate in clinical trials.A survey of more than 1,000 patients showed greater than 70% n...

Real-time trials may ‘fundamentally transform’ research

An FDA initiative to implement real-world clinical trials could dramatically accelerate the pace at which new treatments become available to patients, according to physicians from...

Q&A: New JAMA resource shows ‘labor of love’ behind clinical trials

JAMA Network announced a new resource called JAMA+ Trials that is “designed to elevate the visibility, accessibility and understanding of trusted clinical trial research across med...

Clinical Trials Were Used as Marketing Ploys for Gabapentin and Other Drugs

By Sukhun KangSome clinical trials aren’t designed to answer scientific questions. They’re designed to market drugs. In our recently published research, my team and I analyzed over...

FDA Makes Moves to Modernize Drug Development, Clinical Trial Paradigm

On April 28, 2026, the Food and Drug Administration (FDA) unveiled two major announcements as part of its initiative to “advance the implementation of real-time clinical trials.” I...

FDA Moves Toward Real-Time Clinical Trial Modernization

On April 28, 2026, the U.S. Food and Drug Administration (“FDA”) announced additional steps in its ongoing initiative to advance real-time clinical trial approaches, including proo...

FDA Moves to Real-Time Clinical Trial Patient Monitoring, Faster Drug Review

WEDNESDAY, April 29, 2026 — The U.S. Food and Drug Administration (FDA) is moving to speed drug development and review by launching real-time clinical trials. The move could soon...

New Trial Prevents Cognitive Decline in Older Cancer Patients

In a groundbreaking multicentric randomized controlled trial, researchers have embarked on a novel exploration of cognitive preservation among older Indian patients with cancer und...

FDA Announces New Real-Time Clinical Trial Initiative to Expedite Development, but at What Cost?

By Mark A. Tobolowsky & James E. Valentine —

<![CDATA[The Difference Between Real-Time Clinical Data Review and Real-Time Clinical Trial Oversight]]>

FDA urges clinical trial sponsors to report the results of their studies

An FDA review of records found that results have not been reported for 30% of registered clinical studies. To remedy this shortfall, the U.S. regulator has sent reminders to 2,200...

Academic Clinical Trials for Rapamycin to Answer Questions on Dosing for Anti-Aging Use

Rapamycin is increasingly prescribed off-label by anti-aging physicians based on animal studies and very limited human data (even including the relatively recent crowdfunded PEARL...

FDA Sends Notices to More Than 2,200 Sponsors Regarding Unpublished Clinical Trial Results

The U.S. Food and Drug Administration (FDA) announced on April 13, 2026, that it sent reminder letters to more than 2,200 drug, biologic, and medical device companies and researche...

Current Clinical Trials of Alzheimer’s Drugs

This month, a group of researchers published an annual report on the clinical trials that are testing drugs for Alzheimer’s disease. Overall, they reported an increase in the numbe...

<![CDATA[ What Design Choices Made the MajesTEC-3 Trial Clinically Compelling?]]>

FDA tests out ‘real-time’ clinical trials; AbbVie closes in on a KRAS biotech

Through two pioneering studies, Amgen and AstraZeneca will share study data with FDA scientists as it’s accrued. Elsewhere, Lilly inked a gene editing deal and Pfizer reported succ...

What Are the Top Drugs in Phase 3 Trials in the U.S.?

What Are the Top Drugs in Phase 3 Trials in the U.S.? Anonymous (not verified) Sat, 05/02/2026 - 14:19 pharmagather item url What Are the Top Drugs in Phas...

<![CDATA[Does FDA's Shift From Two Pivotal Trials to One Represent a Genuine Evolution?]]>

Blockchain Smart Contracts for Automating Clinical Trials: Systematic Review and Proposed System Architecture

Background: Blockchain technologies have revolutionized the financial sector through their ability to generate immutable, cryptographically secure records. Clinical trials and heal...

Innovative Approach Enhances Health Research in Rural Communities

Randomised controlled trials (RCTs) have long been hailed as the pinnacle of clinical research, setting the gold standard for evaluating the efficacy of medical interventions. Howe...