Search results for Clinical Trial

FDA Announces Real-Time Clinical Trial Pilot Program and Proof-of-Concept Studies with AstraZeneca and Amgen

What You Should Know The FDA has launched two proof-of-concept (PoC) real-time clinical trials (RTCT) that report endpoints and data signals to the agency as they occur. AstraZenec...

How To Find A Clinical Trial That Actually Prioritizes Your Safety

If you’ve ever wondered how new medications, treatments or medical devices actually make it to your doctor’s office, the answer almost always starts with clinical trials.

New Trial Prevents Cognitive Decline in Older Cancer Patients

In a groundbreaking multicentric randomized controlled trial, researchers have embarked on a novel exploration of cognitive preservation among older Indian patients with cancer und...

Real-time trials may ‘fundamentally transform’ research

An FDA initiative to implement real-world clinical trials could dramatically accelerate the pace at which new treatments become available to patients, according to physicians from...

FDA announces real-time clinical trials, request for information

The Food and Drug Administration April 28 announced its plan to advance the implementation of real-time clinical trials, which invite participants to supply reports and data to the...

Trial of Novel Bispecific Therapy for Resistant Ovarian Cancer

In a groundbreaking stride against one of oncology’s most formidable challenges, researchers have unveiled promising clinical trial results exploring novel immunotherapeutic strate...

FDA Moves to Real-Time Clinical Trial Patient Monitoring, Faster Drug Review

WEDNESDAY, April 29, 2026 — The U.S. Food and Drug Administration (FDA) is moving to speed drug development and review by launching real-time clinical trials. The move could soon...

Most patients with pancreatic cancer not offered clinical trials

Most patients with pancreatic cancer report they were never offered the opportunity to participate in clinical trials.A survey of more than 1,000 patients showed greater than 70% n...

<![CDATA[The Difference Between Real-Time Clinical Data Review and Real-Time Clinical Trial Oversight]]>

Pragmatic Trials

Publisher: The New England Journal of Medicine Published: 2016 This analysis explains the methods used for trials that inform a clinical or policy decision by providing evidence...

First Human Trial of OSCA Therapy for Knee OA

In a groundbreaking advancement poised to transform the management of degenerative joint diseases, researchers have unveiled the first-in-human, multicenter phase I clinical trial...

FDA Moves Toward Real-Time Clinical Trial Modernization

On April 28, 2026, the U.S. Food and Drug Administration (“FDA”) announced additional steps in its ongoing initiative to advance real-time clinical trial approaches, including proo...

A Randomized Trial of Colonoscopy versus Fecal Immunochemical Testing versus Usual Care in the Detection of Colorectal C...

FDA Announces New Real-Time Clinical Trial Initiative to Expedite Development, but at What Cost?

By Mark A. Tobolowsky & James E. Valentine —

FDA Makes Moves to Modernize Drug Development, Clinical Trial Paradigm

On April 28, 2026, the Food and Drug Administration (FDA) unveiled two major announcements as part of its initiative to “advance the implementation of real-time clinical trials.” I...

<![CDATA[ What Design Choices Made the MajesTEC-3 Trial Clinically Compelling?]]>

<![CDATA[Pharmaceutical Executive Daily: Zentalis Doses First Patient with Azenosertib in Phase III Trial]]>

FDA tests out ‘real-time’ clinical trials; AbbVie closes in on a KRAS biotech

Through two pioneering studies, Amgen and AstraZeneca will share study data with FDA scientists as it’s accrued. Elsewhere, Lilly inked a gene editing deal and Pfizer reported succ...

<![CDATA[First Patient Dosed with Azenosertib in Aspenova Phase III Trial for Treatment of Ovarian Cancer]]>

Major milestone reached in Oxford University clinical trial

Oxford University Hospitals (OUH) has recruited its 100th patient to the EASi-KIDNEY study, which is evaluating a potential new treatment for chronic kidney disease (CKD).

<![CDATA[FDA Clears Investigational New Drug Application for Phase Ib/IIa Trial of CK0802 in Steroid-Refractory Graft...

Q&A: New JAMA resource shows ‘labor of love’ behind clinical trials

JAMA Network announced a new resource called JAMA+ Trials that is “designed to elevate the visibility, accessibility and understanding of trusted clinical trial research across med...

OIG Greenlights Cost-Sharing Subsidies for Medicare Enrollees in Medical Device Clinical Trial

On March 11, 2026, the Office of Inspector General (OIG) issued Advisory Opinion No. 26-05, concluding that it would not impose sanctions on a medical device company (Requestor) th...

FDA urges clinical trial sponsors to report the results of their studies

An FDA review of records found that results have not been reported for 30% of registered clinical studies. To remedy this shortfall, the U.S. regulator has sent reminders to 2,200...