Social Media Ideas for Clinical Phenotypes

Latest updates for Clinical Phenotypes

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bioengineer.org /1 week ago

Machine Learning Reveals Three Diabetes Patient Types Shaping Heart and Kidney Drug Choices

A real-world study of 9000 patients with type 2 diabetes in China used cluster analysis to identify three clinical phenotypes linked to distinct prescribing patterns of heart- and...

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journals.plos.org /1 month ago

FM-GPT: Bayesian fine mapping for phenome-wide transcriptome-wide association studies

by Travis Canida, Zhenyao Ye, Shao-Hsuan Wang, Hsin-Hsiung Huang, Yezhi Pan, Menglu Liang, Shuo Chen, Tianzhou Ma Transcriptome-wide association studies (TWAS) integrate genome wi...

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genengnews.com /1 day ago

ASHG: Signals Based on Clinical Obesity Show Stronger Links to Cardiovascular Health than Those Linked to BMI

Researchers also developed a clinical obesity polygenic score that combined information from numerous genetic variants, a score that was shown to be significantly associated with B...

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medicalxpress.com /1 month ago

New findings shed light on rare newly identified TCF7L2-related neurodevelopmental disorder

Researchers have completed the largest study to date of TCF7L2-related neurodevelopmental disorder (TRND), a rare genetic condition caused by changes in the TCF7L2 gene, which play...

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journals.plos.org /1 month ago

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

by Miriam C. Aziz, Jennie Wilson, Clement Y. Chow PIGA-CDG is a congenital disorder of glycosylation caused by pathogenic partial loss-of-function variants in the PIGA gene. PIGA...

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journals.plos.org /1 day ago

Meta-analysis of over 8,000 individuals from Hawai‘i and Samoa for genetic associations to cardiometabolic phenotypes

by Bryan L. Dinh, Xinran Wang, Xin Sheng, Peggy Wan, Amit Kumar Srivastava, Take Naseri, Satupa‘itea Viali, Lynne Wilkens, Loïc Le Marchand, Christopher Haiman, Daniel E. Weeks, Ch...

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genengnews.com /1 week ago

Sickle Cell Trait Linked to Distinct Malaria Parasite Variants

A study in Cameroon found that sickle cell trait is associated with distinct malaria parasite genotypes, potentially explaining reduced disease risk despite similar infection rates...

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scitechdaily.com /2 weeks ago

Extreme Human Traits May Have a Simple Genetic Explanation

A study of dozens of human traits suggests that genetic architecture may shift at the extremes. People with unusually high or low cholesterol, blood glucose, body size, and other m...

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healio.com /3 weeks ago

Clinical obesity prevalent in bariatric surgery candidates

New Lancet Diabetes and Endocrinology Commission criteria, which distinguish clinical obesity from preclinical obesity, may better inform patient selection and risk assessment for...

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medicalxpress.com /1 month ago

Cerebral palsy might be a collection of symptoms, not its own disease

Historically, cerebral palsy (CP) was linked largely to events at birth, including prematurity or temporary loss of oxygen to the brain, but research over the past decade has sugge...

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