Latest updates for Chromatin Accessibility

Fresh curated links around Chromatin accessibility are collected here so marketers can spot useful updates and turn timely ideas into posts faster.

Recent items include:

  • Improved spike-in normalization reveals how active histone modifications relate to transcription
  • Chromatin stability safeguards mitochondrial homeostasis and restrains TORC1 signaling
  • Systematic multivariate analysis of chromatin complex dependencies reveals Set1C/COMPASS as a melanoma-enriched epigenet

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bioengineer.org /1 month ago

Improved spike-in normalization reveals how active histone modifications relate to transcription

Chromatin, the molecular packaging system that compacts DNA inside the nucleus, is not merely a passive storage device. By loosening or tightening access to genetic material, it he...

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journals.plos.org /2 weeks ago

Chromatin stability safeguards mitochondrial homeostasis and restrains TORC1 signaling

by Vinoth Sigamani, Mohd Yousuf, Daniel L. Johnson, Brian D. Strahl, R. Nicholas Laribee Chromatin is dynamically regulated in response to nutrient flux to promote the transcripti...

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journals.plos.org /1 month ago

Systematic multivariate analysis of chromatin complex dependencies reveals Set1C/COMPASS as a melanoma-enriched epigenet...

by Luisa Quesada Camacho, Mohammad Fallahi-Sichani Epigenetic dysregulation is a common feature of cancer. It creates vulnerabilities arising from an increased reliance on chromat...

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journals.plos.org /2 weeks ago

DeCTCF: Decoding CTCF binding sequences by leveraging predicted epigenomic features

by Lu Chai, Jie Gao, Tinghe Guo, Teer Ba, Zihan Li, Junjie Liu, Yong Wang, Lirong Zhang CTCF is a key architectural protein with diverse roles in genome organization and gene regu...

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journals.plos.org /2 weeks ago

HiFIseek: Gene-specific enrichment of high-impact mutations in associated genomic regions

by Rafael Riudavets Puig, Denise G. O’Mahony, Ina Skaara Brorson, Ksenia Sokolova, Vessela N. Kristensen, Anthony Mathelier Transcription is regulated through the sequence-specifi...

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journals.plos.org /2 weeks ago

Epigenetic maintenance of PRC2-repressed chromatin requires RTT109 but not H3K56 acetylation

by Rochelle E. Yap, Felicia Ebot-Ojong, Abigail J. Ameri-Solanky, Zachary A. Lewis In animals, plants, and some fungi, Polycomb Repressive Complex 2 (PRC2) catalyzes trimethylatio...

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journals.plos.org /1 month ago

Tcf15 promotes an open nucleolar chromatin state to safeguard ribosome biogenesis and genome stability in mouse embryoni...

by Yu-ping Dong, Yi-Min Chen, Min Tang, Hu Zhou, Lin Wang, Ping Zheng Embryonic stem cells (ESCs) exhibit a hyperactive chromatin state at ribosomal RNA (rRNA) genes, which not on...

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journals.plos.org /2 weeks ago

The histone methyltransferase complex subunit RBBP5 serves as a central epigenetic regulator of proteostasis dynamics

by Syeda Kubra, Michelle Sun, William Dion, Yu Bian, Ahmet Catak, Hannah Luong, Haokun Wang, Yinghong Pan, Jia-Jun Liu, Aishwarya Ponna, Lijun Liu, Ian Sipula, Jian-Hua Luo, Michae...

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bioengineer.org /1 week ago

New Nanoscale Genome Mapping Tool Pinpoints Causal Autoimmunity Variants

An Oxford-developed single-allele chromatin mapping platform called MCCv identifies causal noncoding variants in autoimmune disease and reveals that a neo-CTCF site blocks super-en...

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bioengineer.org /1 month ago

How Cancer-Causing 3D Chromatin Remodeling Begins and Shapes Disease

Cancer does not merely rewrite the genetic letters of the genome; it can also reorganize the vast three-dimensional structure in which those letters are stored. A new review by Fra...

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nanowerk.com /1 month ago

Researchers discover DNA organization is key to tissue regeneration

Researchers show that long-range chromatin loops help control tissue regeneration, revealing a direct role for 3D genome organization in regenerative processes.

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Sources covering Chromatin Accessibility

bioengineer.org

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journals.plos.org

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journals.plos.org

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journals.plos.org

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nanowerk.com

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