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rna-seqblog.com /1 month ago

PhytoCell – an ensemble learning framework for identifying cell states in plant scRNA-seq data

PhytoCell uses machine learning with RNA sequencing to identify marker genes and classify plant cell subpopulations, improving accuracy in complex single-cell datasets...

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journals.plos.org /1 day ago

Fully synthetic replication of complex real biological cell clusters using a novel cluster-based ‘Rosetta-Routine’ compu...

by Bradley Mason, Laura Justham, Liam Whitby, Alison Whitby, Stuart Scott, Samuel Nti, Jon Petzing Flow cytometry (FC) is essential for the precise quantification and characterisa...

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rna-seqblog.com /1 month ago

scSurvival – Single-Cell Survival Analysis of Clinical Cancer Cohort Data at Cellular Resolution

RNA sequencing combined with single-cell analysis enables scSurvival to link specific tumor cell populations to patient risk, improving survival prediction and revealing drivers of...

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scienceblog.com /3 weeks ago

New Method Reads a Cell’s Genes Without Killing It

Every few minutes, a living cell does something quietly extraordinary: it sheds tiny membrane bubbles into the fluid around it. These extracellular vesicles carry molecular cargo (...

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genengnews.com /1 month ago

Machine Learning and Single-Cell Technology Combined to Drive High-Performance Cell Line Development

The collaboration brings together OneCyte's proprietary single-cell platform for high-throughput and high-speed clone selection with Kemp Proteins' molecular engineering capabiliti...

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genengnews.com /1 month ago

Method Identifies Cellular Makeup of Microenvironments Favoring Tumor Metastasis

Researchers developed a method, SAMENT, that selectively labels cells encountered by cancer cells during metastasis, revealing the cellular makeup of tissues supporting metastatic...

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labiotech.eu /1 month ago

AI in single-cell analysis: solving the interpretation gap

Single-cell omics is reshaping drug discovery, but turning complex data into biological insight remains slow. AI may help close the annotation gap. The post AI in single-cell analy...

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letlifehappen.com /1 month ago

Unusual Tumor Cells May Be Overlooked Factors in Advanced Breast Cancer

From: cornell.edu An enigmatic type of circulating tumor cell called a dual-positive (DP) cell is associated with shorter survival time in patients with advanced breast cancer, acc...

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journals.plos.org /1 month ago

Cell type annotation for scATAC-seq via DNA large language model and graph domain adaptation

by Yan Liu, Sheng Guan, He Yan, Long-Chen Shen, Ji-Peng Qiang, Guo Wei Single-cell ATAC-seq (scATAC-seq) enables the exploration of chromatin accessibility at single-cell resoluti...

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journals.plos.org /3 weeks ago

Partial domain adaptation enables cross domain cell type annotation between scRNA-seq and snRNA-seq

by Xiran Chen, Quan Zou, Qinyu Cai, Xiaofeng Chen, Weikai Li, Yansu Wang Accurate cell type annotation across datasets is a key challenge in single-cell analysis. snRNA-seq enable...

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genengnews.com /2 weeks ago

Cellares and ProTgen Automate Manufacturing of Progenitor T-Cell Therapy for Blood Cancer

The partnership will automate manufacturing and quality control of ProT-096, ProTgen’s personalized progenitor T-cell therapy for refractory leukemia and other hematologic malignan...

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multiple-sclerosis-research.org /1 month ago

Counting cell in blood as a predicitve factor for disease activity

This paper argues that if you look at blood cell counts it may help about look at disease activity. This view is perhaps abit controversial as there have been many studies looking...

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genengnews.com /1 month ago

New Single‑Cell Platform Tracks RNA and Protein in Immune Signaling

CIPHER‑seq is a single‑cell method that measures RNA and proteins simultaneously, exposing gaps in cytokine signaling and reducing mitochondrial stress signatures to give a clearer...

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journals.plos.org /2 weeks ago

The differentiation of myeloid progenitors is effected by cascading waves of coordinated gene expression that remodel ce...

by Andrea Repele, Joanna Handzlik, Nimasha Samarawickrama, Trevor Long, Sunil Nooti, Veena Potluri, Yen Lee Loh, Manu The differentiation of hematopoietic progenitors into special...

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