A microfluidics-free route to encapsulating cells into premade uniform hydrogel microcapsules
Tiny hydrogel capsules let labs grow cells in tissue-like 3D conditions using simple tools, making advanced cell culture cheaper and more accessible.
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Tiny hydrogel capsules let labs grow cells in tissue-like 3D conditions using simple tools, making advanced cell culture cheaper and more accessible.
As cell therapy developers push toward commercial-scale manufacturing, bioprocessing experts rethink how hematopoietic stem cells are isolated. Emerging buoyancy-based technologies...
OrganaBio’s new San Diego cell processing site expands access to fast PBMC isolation and cryopreservation, thus improving quality, consistency, and supply chain surety for these vi...
It only works for a few divisions thanks to a lot of added materials.
Next-generation instruments improve rare-cell detection, sterility control, biosafety, and throughput for translational applications. The post Advanced Cell Sorting Balances Precis...
From chemical building blocks, scientists have created synthetic cells that have most of the hallmarks of life.
This cell-like structure can grow, feed, divide and compete. Researchers ponder what it means for the future of synthetic biology and our definition of “life.”
Cells behave like crowded cities, yet many crucial molecular conversations have been impossible to watch directly in real time. Traditional microscopy often averages enzyme activit...
This language is remarkable coming from a journal often considered the third most important in the world for biology. Source
Made Scientific Inc., a clinical- and commercial-stage cell therapy contract development and manufacturing organization (CDMO), and Pluristyx, a provider of cell (iPSC) platform te...
RNA sequencing workflows using preserved cells enable flexible sample collection and support reproducible single-cell analyses across multiple laboratories and processing platforms...
The aim of the partnership is to provide a platform delivering high-end performance with an optimal cost-of-goods and price-per-dose model to ease scale-up, commercial strategy, an...
In a groundbreaking advancement poised to revolutionize stem cell research and biomanufacturing, a team of scientists has unveiled a novel protocol that enables the direct inoculat...
TAP-seq combines genome editing with targeted RNA sequencing to enable sensitive and cost-effective single-cell functional genomics screens...
Cytomos says its benchtop cell analytics intelligence system combines the compact Celledonia analyzer with the sensors of the AuraCyt modules to transform complex cellular data int...
A new feeder cell line multiplies NK cells by more than 100,000-fold in one month, making it easier to produce these therapeutic cells at commercial quantities and thus develop off...
The diversity of materials and manufacturing methods used to make cell therapies is proving to be a challenge for an industry looking to standardize production. Researchers say AI,...
A genome-scale CRISPRi atlas maps transcriptional consequences for 11,692 gene perturbations across more than 2.5 million human iPSCs. The resource reveals regulators of metabolism...
Circio and Tcelltech will combine Circio's circVec circular RNA expression technology with Tcelltech's non-viral, high-cargo capacity nanoSMAR vector platform and evaluate the comb...
In a landmark collaboration poised to shape the future interface between scientific publishing and artificial intelligence, Rockefeller University Press (RUP) has announced a pione...
by Bradley Mason, Laura Justham, Liam Whitby, Alison Whitby, Stuart Scott, Samuel Nti, Jon Petzing Flow cytometry (FC) is essential for the precise quantification and characterisa...
D&D‑seq uses a base editor–nanobody fusion to record DNA–protein contacts at single‑cell resolution. The method maps transcription factor and chromatin-remodeling proteins. The...
As more than 100 clinical trials test human pluripotent stem cell-derived therapies, researchers are shifting focus from proving large-scale production is possible to building stan...
As TSC-101 is advanced toward a pivotal trial, which is expected to begin later this year, Cellares’ manufacturing platform is being evaluated as a scalable and economical path to...
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