Denosumab reduces osteoarthritis risk more than bisphosphonates
Older adults with osteoporosis may have decreased risk for osteoarthritis if they initiate therapy with denosumab compared with an oral bisphosphonate, according to study data publ...
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Older adults with osteoporosis may have decreased risk for osteoarthritis if they initiate therapy with denosumab compared with an oral bisphosphonate, according to study data publ...
A Hong Kong study of 121,492 older adults links nitrogen-containing bisphosphonates for osteoporosis to a 16% lower Alzheimer's disease risk.
Researchers have been working towards practical approaches to inhibiting RUNX2 activity as a way to slow age-related loss of bone mineral density. Bone extracellular matrix is cons...
A preclinical study in post-menopausal bone loss mouse models found that CADD522, a small-molecule drug targeting RUNX2, protected against osteoporosis, prevented fat gain, and rev...
An experimental compound called AP503 significantly strengthened bones in mice by activating GPR133, a receptor that boosts bone formation while slowing bone loss. Because the same...
Widely used osteoporosis drugs were associated with a lower risk of Alzheimer’s disease and related dementias in a study of more than 120,000 older adults. A medication already pre...
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