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journals.plos.org /1 month ago

Biomarker discovery and patient stratification in pancreatic cancer using incomplete multi-omics data

by Alejandra Paja-García, Rafael Romero-Becerra, Tero Aittokallio, Alberto López Pancreatic ductal adenocarcinoma (PDAC), with a 12% 5-year survival rate, is the most aggressive t...

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academyhealth.org /2 weeks ago

AcademyHealth Releases Compendium of Cancer Biomarker Initiatives: A Central Repository for Cancer Biomarker Testing Res...

AcademyHealth Releases Compendium of Cancer Biomarker Initiatives: A Central Repository for Cancer Biomarker Testing Resources AcademyHealth’s Scaling Cancer Biomarker Test...

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nanowerk.com /4 weeks ago

Laser-powered method detects elusive cancer biomarkers in minutes

A light-induced detection method rapidly measures tiny amounts of the colorectal cancer biomarker CEACAM-5 in blood plasma, revealing that it forms nanoscale aggregates.

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academyhealth.org /1 month ago

AcademyHealth Releases Strategic Roadmap for Advancing Cancer Biomarker Testing at Scale

AcademyHealth Releases Strategic Roadmap for Advancing Cancer Biomarker Testing at Scale For patients facing uncertainty or fear around a cancer diagnosis, cancer biomarker...

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multiple-sclerosis-research.org /1 month ago

Biomarker BS…OK it’s disappointing

Neurofilament assay is used as a marker of nerve damage or inflammation induced nerve damage/inflammatory activity, and the people doing these assays have been part of a biomarker...

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genengnews.com /1 month ago

The Emerging Power of Mass Spectrometry in Oncology

Novel approaches are urgently needed to improve availability of diagnostic assays, and recent efforts have shifted toward uncovering the biological pathways and molecular profiles...

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genengnews.com /2 weeks ago

Investigating Prions and Protein Aggregation at High Sensitivity and Throughput

With no cure available for prion diseases, researchers are striving to improve assay sensitivity and exploit the benefits of real-time monitoring to support the development of bett...

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journals.plos.org /1 week ago

Genome-Wide DNA methylation profiling of tissue-plasma pairs identifies Novel cfDNA biomarkers for the diagnosis of gast...

by Hailing Ou, Jinli Miao, Fusheng Ling, Jie Gao, Tingan Wang, Zhihua Ye, Chunbo Zhang, Mingwei Huang, Yuzhou Qin Screening for gastric cancer (GC) is critical for improving patie...

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scitechdaily.com /1 month ago

Researchers Test a New Way To Find Pancreatic Cancer Before It’s Too Late

An experimental blood test could help detect early pancreatic cancer and precancerous changes, guiding decisions about further testing. People at high risk of pancreatic cancer are...

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genengnews.com /2 days ago

Proteins Circulating in Blood Linked to Future Risk of Prostate Cancer

The results of a large prospective proteomic study have associated proteins linked with the immune system, cell adhesion, blood vessel formation, and known prostate cancer genes, t...

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genengnews.com /2 weeks ago

From Discovery to Development

The articles in this eBook examine key trends driving this transformation, from AI-enabled discovery and experimental validation to advanced cell, gene, and biologic platforms, and...

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genengnews.com /3 weeks ago

Watching Cancer Proteins in Real Time, with Help from Rare Earth Elements

A long-duration single-molecule imaging platform from the Broad Institute and MIT has revealed unexpected stability in homodimers of HER3, one of the most enigmatic members of the...

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bioengineer.org /3 hours ago

Blood Proteins Predict ALS Years Before Symptoms Strike

A large prospective UK Biobank study of 52,584 adults identified nine plasma proteins, led by neurofilament light chain, that predict ALS onset up to a decade before symptoms, with...

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genengnews.com /1 month ago

Consolidating Antibody Discovery Data with an AI Platform

The Sapio Scientific AI platform gives scientists a single, structured environment where experimental records connect directly to client deliverables and where time spent on data c...

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parkinsonsnewstoday.com /1 month ago

Candidate biomarkers may help track Parkinson’s across disease stages

Researchers identified candidate biomarkers in spinal fluid and blood that showed different patterns among healthy controls, people in a prodromal group at risk of Parkinson’s, and...

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labiotech.eu /3 weeks ago

Changing with the times: what is the future of biomarkers in neurology?

Biomarkers that reflect the brain’s workings have been difficult to pin down in neurology studies, but the field has come a long way. The post Changing with the times: what is the...

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rna-seqblog.com /3 days ago

Transcripta Bio Announces Research Collaboration to Advance Discovery of New ALS Treatments

Transcripta Bio and Mayo Clinic will combine single-cell RNA sequencing with AI-driven analysis of patient-derived ALS tissue to identify disease signatures and potential therapeut...

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genengnews.com /1 month ago

The Multi-Attribute Method (MAM) as a Biologics Lifecycle Backbone

A more coherent approach: a peptide-mapping LC-HRMS (liquid chromatography-high resolution mass spectrometry) workflow that can identify and monitor multiple product quality attrib...

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journals.plos.org /2 weeks ago

Omics data discovery agents: Agent-supported retrieval, reanalysis, and synthesis of published omics data

by Alexandre Hutton, Jesse G. Meyer The biomedical literature contains a vast collection of omics studies, yet most published data remain functionally inaccessible for computation...

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rna-seqblog.com /1 month ago

Single Cell Discoveries Acquires TATAA Biocenter to Create an End-to-End Precision Biology CRO

Single Cell Discoveries (SCD), a specialist contract research organization (CRO) focused on discovery transcriptomics, has completed the acquisition of TATAA Biocenter...

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genengnews.com /3 weeks ago

AI and Proteomics Accelerate VAV1 Molecular Glue Discovery

High-throughput proteomics combined with AI-based structural modeling helped researchers discover molecular glues that degrade VAV1. The approach could support new therapies for bl...

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podiatryarena.com /1 month ago

Biomarkers of Healing in Chronic Diabetic Foot Ulcers

‘Ome is where the Wound is: Biomarkers of Healing in Chronic Diabetic Foot Ulcers Marc Glucksman et al April 2017; The FASEB Journal; vol. 31 no. 1 Supplement 780.14 Of...

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kevinmd.com /2 weeks ago

Biomarker testing can find the mutation driving your cancer

“What was cancer, Grandpa?” These were words I hoped to hear from my grandchildren. As a practicing physician for over forty-five years, I wasn’t sure whether futuristic care would...

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rna-seqblog.com /2 weeks ago

Novel biosensor uses DNA ‘barcodes’ to uncover disease signals in cells

RNA sequencing can read Detectron-generated DNA barcodes, enabling scalable detection of specific RNA signals associated with infection, gene activity and other cellular processes....

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