Latest updates for Bioinformatics Databases

Fresh curated links around Bioinformatics databases are collected here so marketers can spot useful updates and turn timely ideas into posts faster.

Recent items include:

  • RNAffinityDB – a curated database of experimental RNA–protein binding affinities
  • DyME: An MD-based engine exploiting HTP mutagenesis for protein engineering and recognition mimicry
  • A Google-like search engine for single-cell RNA

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rna-seqblog.com /20 hours ago

RNAffinityDB – a curated database of experimental RNA–protein binding affinities

RNAffinityDB combines over 10,000 experimental RNA-protein binding records, providing a searchable resource that complements RNA sequencing research and supports computational mode...

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journals.plos.org /2 weeks ago

DyME: An MD-based engine exploiting HTP mutagenesis for protein engineering and recognition mimicry

by Pedro M. Guillem-Gloria, Gloria Ruiz-Gómez, M. Teresa Pisabarro Protein recognition mimicry is of great interest in the field of molecular bioengineering and rational design, w...

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nanowerk.com /1 month ago

A Google-like search engine for single-cell RNA

Scientists have built a search engine that can scan data from millions of single cells from thousands of experiments worldwide in seconds. The tool makes it possible to answer prev...

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journals.plos.org /1 month ago

PanDelos-plus: A parallel algorithm for computing sequence homology in pangenomic analysis

by Simone Colli, Emiliano Maresi, Vincenzo Bonnici The identification of homologous gene families across multiple genomes is a central task in bacterial pangenomics traditionally...

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journals.plos.org /2 weeks ago

Omics data discovery agents: Agent-supported retrieval, reanalysis, and synthesis of published omics data

by Alexandre Hutton, Jesse G. Meyer The biomedical literature contains a vast collection of omics studies, yet most published data remain functionally inaccessible for computation...

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journals.plos.org /1 month ago

Domain classification of archaeal proteomes reveals conserved fold repertoire

by R. Dustin Schaeffer, Jimin Pei, Rui Guo, Jing Zhang, Kirill Medvedev, Qian Cong, Nick Grishin Archaea represent one of the three domains of cellular life and yet account for fe...

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journals.plos.org /3 weeks ago

Fast structural search for classification of gut bacterial mucin O-glycan degrading enzymes

by Mert Erden, Tyler Schult, Karin Yanagi, Jugal Kishore Sahoo, David L. Kaplan, Lenore J. Cowen, Kyongbum Lee The Enzyme Commission (EC) numbering scheme provides a hierarchical...

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rna-seqblog.com /1 month ago

PotatoRTD and TomatoRTD: comprehensive reference transcript datasets for accurate transcriptome analysis and isoform dis...

RNA sequencing and Iso-Seq improve potato and tomato transcript annotations, revealing additional isoforms and enabling more accurate analysis of gene expression and alternative sp...

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phys.org /1 month ago

Uniting sequence and structure to map the protein universe across billions of years of evolution

An international team of researchers, including those at the Earth-Life Science Institute (ELSI) at the Institute of Science Tokyo, has developed a protein language model that brin...

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itmedia.co.jp /1 month ago

Google DeepMind、90億通りの全塩基変異の影響を予測した「AlphaGenome Atlas」 学術向けに無償提供

Google DeepMindは、ヒトゲノムで起こり得る約90億通り全ての一塩基変異の影響を事前予測したデータベース「AlphaGenome Atlas」を公開した。影響度を数値化するスコアも導入し、未解明な非コー...

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bioengineer.org /1 month ago

Scientists characterize genetic variants across the human intrinsically disordered proteome

Variant effect prediction has entered a new phase, but one of biology’s largest blind spots remains stubbornly difficult to resolve. Computational tools have become increasingly ef...

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rna-seqblog.com /2 weeks ago

DeCoRE – a computational method to resolve RNA structural heterogeneity from RNA structure probing data by direct RNA se...

Direct RNA sequencing with DeCoRE reveals alternative RNA structures and folding dynamics at single-nucleotide resolution, providing a detailed view of transcript-level structural....

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rna-seqblog.com /1 month ago

Benchmarking RNA sequencing for more accurate alternative splicing analysis

RNA sequencing benchmarking across 42 laboratories identifies data quality, sequencing depth, and bioinformatics choices that improve alternative splicing and isoform analysis...

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rna-seqblog.com /1 week ago

RiboBA improves detection of hidden protein-coding regions using ribosome profiling

RiboBA improves ribosome profiling and RNA sequencing analysis by correcting experimental biases, enabling more accurate identification of hidden protein-coding regions and transla...

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bioengineer.org /1 month ago

New Microhaplotype Databases and Tools Reveal Crop Genetic Diversity

Tiny DNA Signatures Give Crop Breeders a Sharper View of Hidden Genetic Diversity Plant breeders have gained a new way to see genetic variation that standard DNA markers can miss....

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rna-seqblog.com /1 week ago

Lexogen and Mithrl connect RNA-Seq library prep to AI-powered biological interpretation

Lexogen and Mithrl integrate RNA sequencing with AI-driven biological interpretation, enabling researchers to analyze gene expression data faster and connect results with existing...

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journals.plos.org /1 month ago

Balanced DNA interpolation improves learning of genetic distance-informed embeddings in plants

by Lara M. Kösters, Kevin Karbstein, Ladislav Hodač, Laura Albreht, Elvira Sahuquillo Balbuena, Daniel Botello, Olivier Hardy, Phebian Odufuwa, Eva Pardo Otero, Aireen Phang, Manue...

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medium.com /1 week ago

AI Meets Biology: How Machine Learning Is Transforming Bioinformatics and Microbiology in 2026

From genomic foundation models to intelligent microbiome analysis, artificial intelligence is reshaping how scientists understand life.Continue reading on Medium »

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Sources covering Bioinformatics Databases

bioengineer.org

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journals.plos.org

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medium.com

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phys.org

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rss.itmedia.co.jp

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nanowerk.com

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