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by Paulyna Magaña, Piraveen Gopalasingam, Jennifer R. Fleming, Oleg Kovalevskiy, Augustin Žídek, ThankGod Echezona Ebenezer, Agata Laydon, Roz Onions, Eva Akurut, Syed Muktadir Al...
New OpenAI life sciences tools integrate RNA sequencing analysis, quality control, annotation, and bioinformatics workflows into a unified platform for genomics and research applic...
Formulating software for the study of plant genomes
RNA sequencing supports space biology research by enabling transcriptome-wide analysis of gene expression changes associated with spaceflight and adaptation to space environments.....
STGBench generates realistic paired DNA and RNA sequencing datasets with known genetic alterations, enabling accurate benchmarking of spatial genomics and transcriptomics analysis....
by Christos A. Ouzounis
by Arne Elofsson, Nir Ben-Tal We have seen more progress in computational biology for macromolecules in the last five years than we experienced in the five preceding decades. Thus...
by Mark Alber, Marc R. Birtwistle, Stacey D. Finley, Pedro Mendes
This Parse Biosciences and bit.bio alliance combines single-cell RNA sequencing and causal transcriptomics to map transcription factor-driven cell identity, enabling improved disea...
In the ever-evolving field of genomics, a significant leap has been achieved with the introduction of the PGS Browser, a novel public platform designed to transform the way researc...
Executive SummaryContinue reading on Medium »
by Jean Fan Since the founding of PLOS Computational Biology 20 years ago, genomics research has advanced at a remarkable pace. In this 20th anniversary commentary, as an Editor f...
by Noam Teyssier, Alexander Dobin Modern genomics produces billions of sequencing records per run, which are typically stored as gzip-compressed FASTQ files. While this format is...
by Holly A. Huber, Stacey D. Finley Computational models in systems biology are often underdetermined—that is, there is little data relative to the complexity and size of the mode...
MERCURIUSâ„¢ 1536 DRUG-seq brings RNA sequencing to large-scale compound screening, enabling efficient gene expression profiling... The post Alithea Genomics launches early access...
by Mark Alber, Amber Smith, Reinhard Laubenbacher, Roeland M. H. Merks
Developing software to reveal large genetic changes that lead to cancer
Proteins lie at the heart of biological function and industrial innovation, representing a vast frontier for scientific discovery and application. Engineering proteins to enhance o...
The toolkit turns complex scientific workflows into agent-executable tasks and has applications across protein structure prediction, molecular docking, generative chemistry, genomi...
Advances in end-to-end multiomics platforms and the underlying scientific knowledge now enable faster and more precise biomarker discovery, mechanistic insight generation, and ther...
The Blank Bio and PacBio collaboration combines long-read RNA sequencing and AI foundation models to improve biomarker discovery, patient stratification, and precision... The post...
RNA sequencing joins genomic, proteomic, and clinical data in the expanded NIH All of Us database, creating an unprecedented resource for precision medicine research...
Jill P. Mesirov, PhD, a luminary in the worlds of mathematics and computational biology, has embarked on a new chapter in her distinguished career by joining the Sanford Burnham Pr...
A groundbreaking analysis of 173,303 exomes and genomes from the Pakistan Genome Resource (PGR) has unveiled compelling insights into the genetic architecture of human diseases and...
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