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journals.plos.org /1 month ago

Outbreaks of fluconazole-resistant Candida parapsilosis are driven by low-biofilm-producing isolates...

by Farnaz Daneshnia, Deepika Gunasekaran, Sean Bergin, Lisa Lombardi, Austin M. Perry, Liuyang Cai, Louise A. Walker, Tibor Nemeth, Süleyha Hilmioglu-Polat, Letal I. Salzberg, Aref...

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journals.plos.org /2 weeks ago

A joint mixture Tobit method with latent microbial abundance improves detection of microbiome–disease associations in ze...

by Junrong Deng, Dong Chen, Siyuan Shen, Yuyang Zhou, Hanyu Cui, Yu Qiu, Qiming Li, Yue-Qing Hu Zero inflation remains a major challenge in microbiome differential abundance analy...

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bioengineer.org /1 month ago

A Bacillus Probiotic Failed to Rescue Baby White Seabass From a Risky Microbial Window

In the windowless hatchery tanks of Hubbs-SeaWorld Research Institute in San Diego, thousands of newly hatched white seabass drift through their most dangerous weeks of life — and...

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bioengineer.org /3 days ago

Morphological and phylogenetic analysis identifies four new Distoseptispora species in southern China

A morpho-phylogenetic study identified four new Distoseptispora species from dead branches in Fujian, Jiangxi and Yunnan using microscopic traits and combined ITS, LSU, RPB2 and TE...

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bioengineer.org /4 days ago

Sal(E) resistance gene widespread in emerging Staphylococcus nepalensis

A global genomic analysis indicates that the sal(E) resistance gene is deeply conserved in Staphylococcus nepalensis, while acquired resistance traits vary across lineages found in...

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bioengineer.org /1 month ago

Seasonal Shifts in Shitalakshya River Microbes and Antibiotic Resistance Revealed by Metagenomics

Bangladesh River’s Dry-Season Crisis Is Selecting for Microbes Built to Survive Pollution A river supplying drinking water to millions of people in Dhaka undergoes a dramatic micro...

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bioengineer.org /1 month ago

Lung Bacteria Found to Worsen Influenza Through a Metabolic Trap in Immune Cells

The community of bacteria living deep within the lungs, long regarded as sparse and relatively inconsequential compared with the dense microbial ecosystems of the gut, is emerging...

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journals.plos.org /1 month ago

The 100 Diatom Genomes Project

by Thomas Mock, Gust Bilcke, Eliott Flaum, Shunan Fu, Lilian Hoch, Kevin Moog, Nadine Rijsdijk, Elizabeth C. Ruck, Ian W. Bishop, Carole Duchene, Reuben Gilbertson, Amanda Hopes, C...

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bioengineer.org /1 week ago

Scientists Build Screening Toolkit to Find Bait Ligands for Antibacterial Protein Degradation Drugs

Researchers have developed fluorescence polarization and thermal shift screening methods to identify small-molecule bait ligands for the bacterial ClpC N-terminal domain, a key ste...

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journals.plos.org /1 month ago

The SigD regulon of Mycobacterium abscessus determines cell envelope composition and antibiotic susce...

by Sean R. Jones, Kelly Maune, Kelley Hurst-Hess, Pallavi Ghosh A major determinant of the exceptional intrinsic resistance of M. abscessus is the lipid-rich cell envelope, yet th...

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journals.plos.org /1 month ago

Structural insights into the outer membrane proteins PorA, OMP50 and Cj0034c from native Campylobacter jejuni&l...

by Zhemin Zhang, William D. Gregor, Muslum Ilgu, Yue Yin, Philip A. Klenotic, Qijing Zhang, Edward W. Yu Bacterial outer membrane proteins (OMPs) are critical players in host–path...

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journals.plos.org /1 month ago

High-throughput virus quantification using cytopathic effect area analysis

by Michael J. Murphy, Steven Mazur, Elena N. Postnikova, Brett P. Eaton, Gregory A. Kocher, Winston Chu, Matthew G. Lackemeyer, Syed Qasim Gilani, Jens H. Kuhn, Michael R. Holbrook...

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bioengineer.org /1 month ago

Hidden Microbes Inside Mung Bean Show Striking Stress Tolerance and Fungal-Fighting Power

Deep inside the seeds and roots of Ethiopia’s mung bean plants, researchers have uncovered a collection of bacteria that may reshape how farmers protect and grow crops in some of t...

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journals.plos.org /2 weeks ago

Combined lactate- and phosphate-dependent cytoplasmic acidification is associated with Mycobacterium tuberculosis growth...

by Adam P. Kibiloski, Shelby J. Dechow, Bassel J. Abdalla, Heather M. Murdoch, Anna D. Tischler, Robert B. Abramovitch Mycobacterium tuberculosis (Mtb) cultured in minimal medium...

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bioengineer.org /3 weeks ago

T Cell Receptor Sequencing Reveals Immune Fingerprints in Children with Mycoplasma Pneumonia

Mycoplasma pneumoniae has long been recognized as one of the most common bacterial causes of community-acquired pneumonia in children, yet the way a child’s immune system responds...

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journals.plos.org /1 month ago

Polymorphisms in a bacterial signalling pathway alter evolutionary routes of antibiotic resistance in Escherich...

by Chetna Yelpure, Saillesh Chinnaraj, Kush Topiwala, Jay Phadke, Nishad Matange Antibiotic resistance in bacteria frequently evolves due to mutations in drug-target or detoxifyin...

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bioengineer.org /1 month ago

Genomes of Drug-Resistant Poultry E. coli Reveal Global Genetic Connections

Antimicrobial resistance has become one of the defining health threats of the twenty-first century, and few organisms embody the problem as completely as Escherichia coli. A new co...

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nanowerk.com /3 weeks ago

CRISPR nanodroplets identify multiple mycobacterial species in mixed samples

A genome-informed CRISPR platform combines microfluidic droplets and molecular recognition to distinguish closely related mycobacteria, identifying up to five species in mixed samp...

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bioengineer.org /1 month ago

Root-dwelling bacterium shields mulberries from gray mold while boosting growth

Beneath the soil of a millennium-old mulberry grove in China, scientists have recovered a bacterium that may rewrite how one of the worldÐ²Ð‚â„¢s oldest crops defends itself agains...

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journals.plos.org /1 week ago

The influence of cell morphology on the dynamics and stability of model bacterial communities

by Ing Xhu Lim, Faisal Halabeya, Joshua N. Milstein Understanding how structures arise in microbial communities remains an outstanding challenge in bacterial ecology. When replica...

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journals.plos.org /2 weeks ago

Quantifying antibiotic susceptibility and inoculum effects using transient dynamics of Pseudomonas aeruginosa&l...

by Sarah Sundius, Jennifer Farrell, Kelly L. Eick, Rachel Kuske, Sam P. Brown Antibiotics are a cornerstone of modern medicine, targeting pathogen cells by disrupting essential ce...

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bioengineer.org /3 days ago

MRSA virulence-factor peptide combination shows strongest immune-response profile in single-donor burn-patient cell stud...

An exploratory single-donor ex vivo study found that the A2-B-H MRSA peptide combination had the strongest integrated immune-response profile, but it did not test clinical protecti...

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journals.plos.org /3 weeks ago

A trade-off between fungal biofilm formation and persistence in the host

by Shannon Esher Righi Fungal biofilm formation has long been considered an important virulence trait. A new study on Candida parapsilosis outbreak isolates in PLOS Biology challe...

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medium.com /1 week ago

AI Meets Biology: How Machine Learning Is Transforming Bioinformatics and Microbiology in 2026

From genomic foundation models to intelligent microbiome analysis, artificial intelligence is reshaping how scientists understand life.Continue reading on Medium »

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