Why Observational Studies Lie to You
If you’ve spent five minutes paying attention to medical news, you’ve undoubtedly seen the headlines: “People who take statins have 30% fewer heart attacks!” or “Breast cancer scre...
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If you’ve spent five minutes paying attention to medical news, you’ve undoubtedly seen the headlines: “People who take statins have 30% fewer heart attacks!” or “Breast cancer scre...
With 66 percent of U.S. adults, some 131 million people, now taking prescription drugs, and with Medicare drug spending running into the hundreds of billions, it is worth asking ho...
In our first article, we discussed the international regulatory clash between U.S. supplement mandates (21 CFR 111) and foreign food and supplement laws. This gap can lead to inade...
Researchers tracked 2.3 million seniors and found one pill routinely leading to another. Three chains start with drugs you know.
Werth, whose books include The Billion-Dollar Molecule (1994), opens with the 1918 Spanish flu pandemic, which did not spare the U.S., whose doctors wrote millions of prescriptions...
A physician writes a prescription believing the clinical decision has been made. In reality, another decision-making process is just beginning. Between the prescription and the pat...
Pelacarsen didn’t protect heart health despite lowering levels of a protein particle, “Lp(a),” in a large clinical trial — a surprise result with important implications for cardiov...
Cardiologists are struggling to figure out why a drug that should have prevented heart attacks didn’t work at all.
Direct-to-consumer drug advertising has changed dramatically over the past decade. What began as cautious messaging about serious medications has evolved into lifestyle marketing:...
An opinion piece argues that fragmented approvals, slow recruitment and delayed drug access are weakening Canada’s clinical trial sector and limiting patient opportunities. The pos...
MONDAY, Aug. 24, 2026 — Northwestern University economist Chuck Manski studies decision-making amid uncertainty. That prepared him better than many other cancer patients to decide...
WEDNESDAY, Aug. 26, 2026 — In January, Jeff La Marca got a prescription for the popular weight loss drug Zepbound. But he couldn’t afford the $750 monthly price tag. “I thought, ‘T...
This structural problem calls for a structural solution, requiring no new science, regulation, or data. The post The Trials Were Always There — Patients Just Couldn’t Find Them ap...
Clinical trial statistics tell us where investigational drugs are tested. They do not tell us who owns the assets, who uses the evidence to obtain regulatory approvals or who captu...
Doctors were hopeful the drug, which was being tested in a large clinical trial by Novartis, was going to be a powerful new tool to fight heart disease.
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