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In a groundbreaking study published in Nature, researchers have uncovered a pivotal role of the transcription factor ATF4 in orchestrating the neuronal DNA damage response (DDR), r...
RNA sequencing reveals how ATF6α supports pancreatic beta cell survival and proliferation under chronic stress, offering insight into diabetes-related beta cell loss...
In a groundbreaking study that could redefine therapeutic approaches to one of the deadliest malignancies, pancreatic cancer, researchers have uncovered a novel mechanism by which...
by Maik Mendler, Kristin Krause, Simone Zündorf, Prathamesh Sannak, Petra Tänzler, Sara Stolze, Hirofumi Nakagami, Franziska Turck Epigenetic regulators shape chromatin landscapes...
RNA sequencing with regRNA Capture-seq identified thousands of regulatory RNAs and enabled new strategies to increase expression of disease-related genes using ASOs...
The APOE ε4 variant heavily influences how toxic phosphorylated TDP-43 (pTDP-43) pathology migrates across the central nervous system.
In a groundbreaking study poised to redefine our understanding of neurodegenerative diseases, researchers have uncovered compelling evidence linking the expression of caspase-4 wit...
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