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rna-seqblog.com /1 month ago

Novogene Europe Expands Single-cell Sequencing Capability at Cambridge Omics Centre

Expanded RNA sequencing services at Novogene Europe bring advanced single-cell transcriptomics, bioinformatics, and multiomics support closer to UK researchers studying complex bio...

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asianscientist.com /1 month ago

The New Economics of Population Genomics

Twist Bioscience’s integrated ecosystem of next-generation sequencing tools that drive up throughput and lower cost is powering a new era of population genetics research.

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genengnews.com /1 month ago

10x Clinical Expansion Advances with CLIA Lab Plans, Cleveland Clinic Partnership

Traditionally focused on research tools for academic, government, and industry customers, 10x has moved this year to launch clinical collaborations with top-tier institutions—the m...

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bioengineer.org /4 weeks ago

OneCell CUT&Tag Maps Chromatin, Transcripts and Surface Markers, Revealing Epigenomic Reprogramming

A new single-cell technology is giving researchers an unusually complete view of how individual cells establish and change their identities. Called OneCell CUT&Tag, the method...

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law360.com /2 weeks ago

Fed. Circ. Backs PTAB's Ax Of 10x Genomics Patent Claims

The Federal Circuit declined Wednesday to save claims in a trio of 10x Genomics patents covering nucleic acid analysis methods, affirming decisions from the Patent Trial and Appeal...

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labiotech.eu /1 month ago

Roche’s new gene sequencer on the market: where do current players stand?

Roche's AXELIOS 1 enters next generation DNA sequencing. Can it or rivals unseat Illumina's long-standing market dominance? The post Roche’s new gene sequencer on the market: where...

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rna-seqblog.com /1 month ago

Benchmarking long-read RNA sequencing tools for single-cell and spatial transcriptomics

RNA sequencing benchmark compares long-read bioinformatics tools for single-cell and spatial transcriptomics, helping researchers improve isoform detection and gene...

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rna-seqblog.com /1 month ago

STGBench – sequencing-level spatial DNA-RNA simulation for multimodal and virtual cell-oriented benchmarking of genomic...

STGBench generates realistic paired DNA and RNA sequencing datasets with known genetic alterations, enabling accurate benchmarking of spatial genomics and transcriptomics analysis....

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genengnews.com /5 days ago

Watchmaker Genomics Boosts Manufacturing Capacity with Major Boulder Campus Expansion

The Flatiron Park facility in Colorado will serve as the Watchmaker Boulder Manufacturing Center of Excellence for reagent manufacturing and will house the company’s manufacturing,...

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rna-seqblog.com /4 weeks ago

NextLongIso – a comprehensive Nextflow pipeline for multi-dimensional long-read RNA-seq analysis

NextLongIso provides a unified RNA sequencing pipeline for analyzing transcript isoforms, alternative splicing, promoter usage, and...

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rna-seqblog.com /3 weeks ago

Tidesurf improves RNA velocity analysis for modern single-cell RNA sequencing

Tidesurf improves RNA sequencing analysis by accurately quantifying spliced and unspliced transcripts across 3' and 5' protocols for more reliable RNA velocity estimates...

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journals.plos.org /1 day ago

scGSI: Graph-guided self-supervised integration of paired single-cell multi-omics

by Xiang Chen, Zihan Yang, Xiaoyu Liu, Zhiyi Xie, Wenlu Guo Paired single-cell multi-omics technologies provide direct within-cell correspondence across molecular layers and offer...

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scitechdaily.com /1 month ago

Harvard Scientists Turned a Silicon Chip Into a DNA Factory

Harvard scientists have built a silicon chip that writes DNA using electricity and water, pointing toward a cleaner future for DNA manufacturing and biotechnology. Silicon chips ha...

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genengnews.com /3 weeks ago

Human Cell Atlas at 10: A Decade of Discovery and the Road to HCA 2.0

Marking its 10th anniversary, the Human Cell Atlas reflects on a decade of breakthroughs while charting an ambitious course for the next decade. GEN's Julianna LeMieux, PhD, spoke...

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nanowerk.com /1 month ago

A single chip screens millions of microbes for antimicrobials in days

Polychip integrates six droplet operations on one device, screening millions of microbial interactions and recovering antimicrobial hits in days instead of the months estimated for...

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rna-seqblog.com /1 month ago

Spatial transcriptomics benchmark compares leading platforms

RNA sequencing and spatial transcriptomics were combined to benchmark leading platforms, helping researchers compare how accurately each maps gene activity within complex tissues.....

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bioengineer.org /3 weeks ago

Global Cancer Genomics Enabled by Centralized Processing of Frozen Tumor Tissues

Cancer researchers have unveiled a standardized pathology and molecular workflow designed to solve one of the most difficult problems in international genomics: turning frozen tumo...

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genengnews.com /1 month ago

Single-Cell Atlas Simultaneously Maps 3D Genome Architecture and DNA Methylation

Atlases like this one can provide the labeled, cell-type-resolved training data that artificial intelligence models need to make accurate predictions—a bottleneck that has historic...

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nanowerk.com /1 week ago

A Google-like search engine for single-cell RNA

Scientists have built a search engine that can scan data from millions of single cells from thousands of experiments worldwide in seconds. The tool makes it possible to answer prev...

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journals.plos.org /1 week ago

Characterization of METTL3/14-mediated m<sup>6</sup>A modification in human transcriptome using Nanopore dir...

by Emily Kurtyan, Andrew J. Stein, Kelly J. Abdalla, Zhangerjiao Yuan, Miten Jain, Fadia Ibrahim Post-transcriptional RNA modifications modulate diverse aspects of RNA metabolism....

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genengnews.com /1 month ago

Genome-Scale CRISPRi Atlas Maps Gene Function Across Human iPSCs

A genome-scale CRISPRi atlas maps transcriptional consequences for 11,692 gene perturbations across more than 2.5 million human iPSCs. The resource reveals regulators of metabolism...

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rna-seqblog.com /1 week ago

Lexogen Expands NGS Services with GCLP-Compliant Workflows

Lexogen’s GCLP-compliant RNA sequencing workflows support clinical research with controlled sample handling, documented processing, data integrity, bioinformatics, reporting, and t...

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rna-seqblog.com /2 weeks ago

An end-to-end computational framework for “Record-seq” transcriptional recording data

A new framework adapts RNA sequencing analysis for Record-seq, improving spacer extraction, transcription-unit quantification, normalization, differential expression, and modeling...

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bioengineer.org /2 weeks ago

Improved spike-in normalization reveals how active histone modifications relate to transcription

Chromatin, the molecular packaging system that compacts DNA inside the nucleus, is not merely a passive storage device. By loosening or tightening access to genetic material, it he...

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