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Here is yet another clue about how we are both spiritual and physical beings. The two realms are connected in mysterious and remarkable ways. Source
Traditional gene editing rewrites DNA. But a new approach, called epigenome editing, aims to treat the molecular scars we collect throughout our lives.
Cancer has long been understood as a disease of the genome, driven by mutations that rewire the instructions encoded in DNA. Over the past three decades, however, a parallel truth...
Cancer does not merely rewrite the genetic letters of the genome; it can also reorganize the vast three-dimensional structure in which those letters are stored. A new review by Fra...
by Rochelle E. Yap, Felicia Ebot-Ojong, Abigail J. Ameri-Solanky, Zachary A. Lewis In animals, plants, and some fungi, Polycomb Repressive Complex 2 (PRC2) catalyzes trimethylatio...
Scientists linked early-life stress experience in mice to long-term stress hypersensitivity within the brain’s dopaminergic circuitry, providing a mechanism by which early-life str...
Chromatin, the molecular packaging system that compacts DNA inside the nucleus, is not merely a passive storage device. By loosening or tightening access to genetic material, it he...
A study of worms finds a protein that helps shape the structure of the genome is critical for establishing the identity of some neurons.
Earlier in this series I killed a brain and the memory lived through it. Then I dropped that memory into a fresh brain, and the fresh brain woke up believing a life it never lived...
You are the science news desk of a major English-language science magazine. Complete the task immediately. Never ask the reader what to do, never offer editing options, and never r...
In the earliest hours of a sea lamprey embryo’s life, something remarkable happens. As its cells divide, vast stretches of genetic material—entire chromosomes—are...
A new single-cell technology is giving researchers an unusually complete view of how individual cells establish and change their identities. Called OneCell CUT&Tag, the method...
Jonathan Wells’s review was important, but it only scratches the surface of information in biology outside of the DNA. Source
Researchers reveal that radial glial progenitor lineage progression in cortical organoids differs from the developing mouse brain, highlighting the importance of stem-cell niche si...
A new computational framework that identifies minimal temporary gene-control interventions to steer cells toward desired states while preserving cellular plasticity.
DNA regulatory elements, which control when, where, and to what extent specific genes are turned on or off, can be co-opted by scientists to create gene switches. The post Gene Sw...
SKIN THE ARCHITECT is an interactive installation by LAIDA - the Latvian Architecture and Design Union - created in response to the theme of this year's Tallinn Architecture Bienna...
New findings could change how scientists think about DNA organization, transcription, and genome function.
by Luisa Quesada Camacho, Mohammad Fallahi-Sichani Epigenetic dysregulation is a common feature of cancer. It creates vulnerabilities arising from an increased reliance on chromat...
Cambridge, MA – MIT Media Lab – EmTech Future. Nature has spent roughly 3.8 billion years conducting the most sprawling, creative research and development campaign in history. Evol...
Aging clocks have yet to fulfill their promise, which is to produce a robust measure of biological aging that can be used to rapidly assess the results of potential therapies to sl...
ARCADIA integrates single-cell RNA sequencing with spatial proteomics to reveal how tissue neighborhoods influence B-cell maturation, T-cell activation, and other transcriptional p...
The daily rhythms that govern life on Earth—from the sleep-wake cycles of humans to the emergence of insects from their pupal cases—are orchestrated by an internal molecular timeke...
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